Evidence map›Paper›PMID 39563316›Full record

ArticleCardiovascular diabetology2024

Lipoxin A

Ting Fu, Muthukumar Mohan, Madhura Bose, Eoin P Brennan, Helen Kiriazis, Minh Deo, Cameron J Nowell, Catherine Godson, Mark E Cooper, Peishen Zhao and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiovascular diabetology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Review
  3. Burden and age-specific trends of atrial fibrillation/atrial flutter from 1990 to 2023: a growing challenge among younger and middle-aged adults.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Islet Tissue Macrophages in Immunity Homeostasis and Type 1 Diabetes.Clinical reviews in allergy & immunology · 2025
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ting FuDrug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.ORCID 0009-0003-0387-9962
Muthukumar MohanDepartment of Diabetes, Central Clinical School, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0003-1044-146X
Madhura BoseDepartment of Diabetes, Central Clinical School, Monash University, Melbourne, Victoria, Australia.
Eoin P BrennanDiabetes Complications Research Centre, School of Medicine and Conway Institute, University College Dublin, Dublin, Ireland.ORCID 0000-0003-4908-5474
Helen KiriazisBaker Heart and Diabetes Institute, Melbourne, Victoria, Australia.ORCID 0009-0009-6658-1489
Minh DeoDrug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.
Cameron J NowellDrug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.ORCID 0000-0002-8662-9840
Catherine GodsonDiabetes Complications Research Centre, School of Medicine and Conway Institute, University College Dublin, Dublin, Ireland.ORCID 0000-0003-0655-1041
Mark E CooperDepartment of Diabetes, Central Clinical School, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0001-7785-2488
Peishen ZhaoDrug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.ORCID 0000-0003-0185-0595
Barbara K Kemp-HarperDepartment of Pharmacology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.ORCID 0000-0002-4669-4277
Owen L WoodmanDrug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.ORCID 0000-0003-3759-1396
Rebecca H Ritchie *Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.ORCID 0000-0002-8610-0058
Phillip Kantharidis *Department of Diabetes, Central Clinical School, Monash University, Melbourne, Victoria, Australia.ORCID 0000-0001-6260-1643
Cheng Xue Qin *Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia. Helena.qin@monash.edu.ORCID 0000-0003-2169-2686

Funding

Australian Research Council Future Fellowship FT200100218Diabetes Australia Research Program Y22G-MOHMNational Health and Medical Research Council 1059960National Health and Medical Research Council APP1183737National Heart Foundation of Australia Future Leader Fellowship 102787
6 · The paper itself

Abstract

backgroundDiabetic heart disease may eventually lead to heart failure, a leading cause of mortality in diabetic individuals. The lack of effective treatments for diabetes-induced heart failure may result from a failure to address the underlying pathological processes, including chronic, low-grade inflammation. Previous studies have reported that lipoxin A

methodsSix-week-old male apolipoprotein E-deficient (ApoE

resultsAs expected diabetic mice showed a significant elevation in plasma glycated hemoglobin (HbA

conclusionsThese findings demonstrated that LXA

Indexed as

Diabetes Mellitus, ExperimentalDiabetic CardiomyopathiesLipoxinsVentricular Function, LeftVentricular RemodelingAnimalsAnti-Inflammatory AgentsApoptosisDiabetes Mellitus, Type 1FibrosisInflammation MediatorsMacrophagesMaleMiceMice, Inbred C57BLMice, Knockout, ApoEAnti-Inflammatory AgentsInflammation Mediatorslipoxin A4LipoxinsCardiac fibrosisCardiac inflammationDiabetic cardiomyopathyLipoxin A4Resolution of inflammationSpecialized pro-resolving lipid mediators

Identifiers

PMID39563316
PMCPMC11577589

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.