Evidence map›Paper›PMID 39564519›Full record

ArticleSexual medicine2024

Sexual function following risk-reducing salpingo-oophorectomy: a prospective cohort study.

Åsa Ehlin von Kartaschew, Angelica Lindén Hirschberg, K Gemzell-Danielsson, Angelique Flöter Rådestad

Abstract read
In one paragraph

Article in Sexual medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Åsa Ehlin von KartaschewLIVIO, 115 42 Stockholm, Sweden.ORCID https://orcid.org/0000-0001-6254-3578
Angelica Lindén HirschbergDepartment of Women's and Children's Health, Karolinska Institutet, 117 77 Stockholm, Sweden.
K Gemzell-DanielssonDepartment of Women's and Children's Health, Karolinska Institutet, 117 77 Stockholm, Sweden.
Angelique Flöter RådestadDepartment of Women's and Children's Health, Karolinska Institutet, 117 77 Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Increased access to and indications for genetic testing will lead to more women undergoing risk-reducing salpingo-oophorectomy (RRSO), with a potential impact on sexual function. Aim: Our objective was to prospectively investigate (1) sexual function in women with pathogenic variant (PV) in Methods: A prospective observational follow-up study of 43 Outcomes: Sexual function and testosterone levels following RRSO. Results: Median age in the RRSO group was 42 years at baseline, 55.8% were premenopausal and 53.5% had a history of breast cancer. The RRSO group had significantly lower median FSFI total score ( Clinical implications: The results highlight the need to counsel Strengths and Limitations: The main strength of this study is its prospective design with age-matched controls. Limitation is a small sample size. Conclusion: Our findings show that sexual function deteriorated 1 year after RRSO independent of testosterone levels, and the proportion with impaired sexual function was higher compared to healthy age-matched controls.

Indexed as

BRCAfemale sexual function indexfree androgen indexmenopausal hormone therapyrisk-reducing salpingo-oophorectomysexual functiontestosterone

Identifiers

PMID39564519
PMCPMC11576125

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.