Evidence mapPaperPMID 39564576Full record

ReviewPsoriasis (Auckland, N.Z.)2024

Impact of GLP-1 Receptor Agonists on Psoriasis and Cardiovascular Comorbidities: A Narrative Review.

Kathryn Haran, Chandler E Johnson, Payton Smith, Zoë Venable, Allison Kranyak, Tina Bhutani, Caleb Jeon, Wilson Liao

Abstract readReview
In one paragraph

Review in Psoriasis (Auckland, N.Z.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kathryn HaranDepartment of Dermatology, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0001-8166-4826
Chandler E JohnsonDepartment of Dermatology, University of California San Francisco, San Francisco, CA, USA.ORCID 0009-0009-1450-0579
Payton SmithDepartment of Dermatology, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0001-6505-9773
Zoë VenableDepartment of Dermatology, Golden State Dermatology, Berkeley, CA, USA.
Allison KranyakDepartment of Dermatology, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0003-0017-138X
Tina BhutaniDepartment of Dermatology, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0001-8187-1024
Caleb JeonDepartment of Dermatology, Golden State Dermatology, Berkeley, CA, USA.
Wilson LiaoDepartment of Dermatology, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0001-7883-6439

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoriasis is an immune-mediated skin disease known to be associated with a higher risk of cardiometabolic comorbidities such as hypertension, myocardial infarction, and stroke. GLP-1 receptor agonists (GLP-1RAs) are medications approved to treat type 2 diabetes mellitus and obesity and have been reported to improve psoriasis. As more psoriasis patients start GLP-1RAs for approved indications, it is of interest to understand the impact of GLP-1RAs on both psoriasis and associated cardiovascular risk. In this review, we examine the effect of GLP-1RAs on psoriasis and cardiovascular comorbidities-defined as hypertension, stroke, and myocardial infarction. The majority of case reports and prospective cohort studies found GLP-1RAs improved psoriasis, while two randomized controlled trials showed conflicting results. For cardiovascular disease, most studies found GLP-1RAs reduced systolic blood pressure, total stroke, and myocardial mortality. These results suggest that GLP-1RAs may be a particularly promising treatment for psoriasis patients with diabetes or obesity comorbidities, offering both cardioprotective benefits and potential improvement in psoriatic symptoms.

Indexed as

hypertensionmyocardial infarctionoxidative stressskin diseasestroke

Identifiers

PMID39564576
PMCPMC11575455

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.