Evidence map›Paper›PMID 39567702›Full record

ArticleNature biomedical engineering2025

Clinical validation of a wearable ultrasound sensor of blood pressure.

Sai Zhou, Geonho Park, Katherine Longardner, Muyang Lin, Baiyan Qi, Xinyi Yang, Xiaoxiang Gao, Hao Huang, Xiangjun Chen, Yizhou Bian and 15 more

Registry-linked trialAbstract readValidation Study
PubMed Publisher
In one paragraph

Article in Nature biomedical engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07186491 (Exploring the Application of a Wearable Ultrasound), which is not on this map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07186491 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Exploring the Application of a Wearable Ultrasound (US) Patch Device for Breast Imaging

TypeinterventionalSponsorMassachusetts General HospitalRan2026 to 2027Enrolled50ConditionsBreast Cancer, Breast Abnormalities, Breast Lesion, Breast AsymmetryArmsWearable Ultrasound Patch
3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Article
  2. Article
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  4. Polymer-Based Multiparameter Sensing Integrated Photonic Chip for Health Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Mechanomedicine.Nature reviews bioengineering · 2026
    Article
  18. Article
  19. Feel the force: Biomechanical homeostasis of the cardiovascular system.Journal of translational internal medicine · 2026
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Sai Zhou *Materials Science and Engineering Program, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-9878-877X
Geonho Park *Aiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-1976-4460
Katherine Longardner *Department of Neurosciences, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-5479-2590
Muyang Lin *Aiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-6627-6294
Baiyan QiMaterials Science and Engineering Program, University of California San Diego, La Jolla, CA, USA.
Xinyi YangMaterials Science and Engineering Program, University of California San Diego, La Jolla, CA, USA.
Xiaoxiang GaoAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California San Diego, La Jolla, CA, USA.
Hao HuangAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California San Diego, La Jolla, CA, USA.
Xiangjun ChenMaterials Science and Engineering Program, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0009-0008-8760-956X
Yizhou BianAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California San Diego, La Jolla, CA, USA.
Hongjie HuAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-3792-4894
Ray S WuAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-0561-0508
Wentong YueAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California San Diego, La Jolla, CA, USA.
Mohan LiDepartment of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA, USA.
Chengchangfeng LuDepartment of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0003-3807-9917
Ruotao WangAiiso Yufeng Li Family Department of Chemical and Nano Engineering, University of California San Diego, La Jolla, CA, USA.
Siyu QinDepartment of Electrical and Computer Engineering, University of California San Diego, La Jolla, CA, USA.ORCID http://orcid.org/0000-0001-7103-1953
Esra TasaliDepartment of Medicine, The University of Chicago, Chicago, IL, USA.
Theodore KarrisonDepartment of Public Health Sciences, The University of Chicago, Chicago, IL, USA.
Isac ThomasDivison of Cardiovascular Medicine, University of California San Diego, La Jolla, CA, USA.
Benjamin SmarrShu Chien-Gene Lay Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.
Erik B KistlerShu Chien-Gene Lay Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.
Belal Al KhiamiDivison of Cardiovascular Medicine, University of California San Diego, La Jolla, CA, USA.
Irene LitvanDepartment of Neurosciences, University of California San Diego, La Jolla, CA, USA.
Sheng XuMaterials Science and Engineering Program, University of California San Diego, La Jolla, CA, USA. shengxu@ucsd.edu.ORCID http://orcid.org/0000-0002-3120-4992

Funding

U.S. Department of Health & Human Services | NIH | National Institute of Biomedical Imaging and Bioengineering (NIBIB) 1 R01 EB03346401Wellcome Trust (Wellcome) WT215841/Z/19/Z
6 · The paper itself

Abstract

Options for the continuous and non-invasive monitoring of blood pressure are limited. Cuff-based sphygmomanometers are widely available, yet provide only discrete measurements. The clinical gold-standard approach for the continuous monitoring of blood pressure requires an arterial line, which is too invasive for routine use. Wearable ultrasound for the continuous and non-invasive monitoring of blood pressure promises to elevate the quality of patient care, yet the isolated sonographic windows in the most advanced prototypes can lead to inaccurate or error-prone measurements, and the safety and performance of these devices have not been thoroughly evaluated. Here we describe validation studies, conducted during daily activities at home, in the outpatient clinic, in the cardiac catheterization laboratory and in the intensive care unit, of the safety and performance of a wearable ultrasound sensor for blood pressure monitoring. The sensor has closely connected sonographic windows and a backing layer that improves the sensor's accuracy and reliability to meet the highest requirements of clinical standards. The validation results support the clinical use of the sensor.

Indexed as

Blood PressureBlood Pressure DeterminationBlood Pressure Monitoring, AmbulatoryWearable Electronic DevicesAdultAgedBlood Pressure MonitorsEquipment DesignFemaleHumansMaleMiddle AgedReproducibility of ResultsUltrasonography

Identifiers

PMID39567702

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.