Evidence map›Paper›PMID 39568960›Full record

ArticleMolecular imaging

Joseph Haddad, Selim Demirdelen, Clayton E Barnes, Steven A Leers, Sina Tavakoli

Abstract read
In one paragraph

Article in Molecular imaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joseph HaddadDepartments of Radiology, Division of Cardiothoracic Imaging, University of Pittsburgh, Pittsburgh, PA, USA.
Selim DemirdelenDepartments of Radiology, Division of Cardiothoracic Imaging, University of Pittsburgh, Pittsburgh, PA, USA.
Clayton E BarnesDepartments of Radiology, Division of Cardiothoracic Imaging, University of Pittsburgh, Pittsburgh, PA, USA.
Steven A LeersDepartments of Surgery, Division of Vascular Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
Sina TavakoliDepartments of Radiology, Division of Cardiothoracic Imaging, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0003-0574-3914

Funding

A Molecular Imaging Approach to Immuno-Metabolic Characterization of Vessel Wall MacrophagesK08HL144911 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TAVAKOLI, SINA · 2019 to 2023
$813k
NHLBI NIH HHS K08 HL144911
6 · The paper itself

Abstract

Objective: 2-Deoxy-2-[ Methods: Results: LDH activity was heterogeneous throughout the plaques with the highest activity in medial smooth muscle cells (SMCs). G6PD activity was mostly confined to the medial layer and to a lesser extent to SMCs along the fibrous cap. SDH and IDH activities were minimal in plaques. Plaque regions with increased [ Conclusions: Our study reveals a novel aspect of the metabolic heterogeneity of the atherosclerotic plaques, enhancing our understanding of the complex immunometabolic biology that underlies [

Indexed as

AtherosclerosisDeoxyglucoseGlucoseAnimalsAutoradiographyFemaleFluorodeoxyglucose F18Glucosephosphate DehydrogenaseHumansL-Lactate DehydrogenaseMaleMiceMice, Inbred C57BLPlaque, AtheroscleroticDeoxyglucoseFluorodeoxyglucose F18GlucoseGlucosephosphate DehydrogenaseL-Lactate Dehydrogenase[18F]FDGatherosclerosismacrophagemetabolismvascular smooth muscle cell

Identifiers

PMID39568960
PMCPMC11577107

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.