ArticleTurkish journal of pharmaceutical sciences2024
Evaluation of a Synthetic Polyethyleneimine Based Polymeric Vector for
Article in Turkish journal of pharmaceutical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objectives: Breast cancer is the most common type of cancer among women and the second most common cause of death after lung cancer. The inhibitor of growth (ING) transcript levels are often suppressed in cancer cells, making it a promising candidate for cancer therapy. In this study, we aimed to formulate a polyplex that effectively carries and delivers pING4 to breast cancer cells. Materials and Methods: Polyethyleneimine (PEI)-based non-viral vectors were synthesized and characterized for plasmid DNA delivery. Complexation was achieved Results: Polyplexes carrying the Conclusion: Our findings suggest that
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