Evidence map›Paper›PMID 39571615›Full record

Observational studyVox sanguinis2025

Missed opportunities: Lack of a diagnostic workup of anaemia results in a high prevalence of unidentified anaemia.

Christian Carrier, David Meltzer, Micah T Prochaska

Abstract readObservational Study
In one paragraph

Observational study in Vox sanguinis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christian CarrierPritzker School of Medicine, University of Chicago, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0001-7588-075X
David MeltzerSection of Hospital Medicine, University of Chicago, Chicago, Illinois, USA.
Micah T ProchaskaPritzker School of Medicine, University of Chicago, Chicago, Illinois, USA.

Funding

Short Term Aging-Related Research ProgramT35AG029795 · NIA · UNIVERSITY OF CHICAGO · PI Vineet Arora, DAVID O MELTZER · 2008 to 2026
$1.4M
The Effect of Red Blood Cell Transfusion on Fatigue, Activity and Fatigability in Hospitalized Patients with AnemiaK23HL140132 · NHLBI · UNIVERSITY OF CHICAGO · PI PROCHASKA, MICAH THOMAS · 2018 to 2022
$736k
NHLBI NIH HHS K23 HL140132NHLBI NIH HHS K23HL140132NHLBI NIH HHS L30 HL143548NIA NIH HHS T35 AG029795
6 · The paper itself

Abstract

BACKGROUND AND

objectivesAnaemia is a treatable common condition with various aetiologies and is prevalent in hospitalized patients. However, anaemia is inconsistently worked up and treated in the inpatient setting, in part because there is no standardized inpatient diagnostic and treatment approach to anaemia. Therefore, the objective of this study was to examine the diagnostic approach and prevalence of common aetiologies of anaemia in hospitalized patients and test for an association between aetiologies of anaemia and patient characteristics. MATERIALS AND

methodsThis study is a prospective observational study of hospitalized adult patients with anaemia. Patient laboratory data were used to assess the frequency of anaemia diagnostic workup and common aetiologies of anaemia.

resultsIn a sample of 945 patients (mean age 58 years, 57% female and 72% Black), 30% patients had chronic anaemia, 11% had multifactorial anaemia, 5% had iron deficiency and 37% had insufficient laboratory data to determine their anaemia aetiology (unidentified aetiology). Patients with an unidentified aetiology received fewer transfusions and were more likely to be White, have longer hospital stays and have higher nadir haemoglobin levels.

conclusionA significant portion of hospitalized patients with anaemia did not have an identified aetiology. A standardized diagnostic algorithm could decrease this number and help patients receive appropriate treatment.

Indexed as

AnemiaAdultAgedAged, 80 and overFemaleHospitalizationHumansMaleMiddle AgedPrevalenceProspective Studiesanaemia of chronic inflammationdiagnostic workuptransfusionunidentified anaemia

Identifiers

PMID39571615
PMCPMC11839249

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.