Evidence mapPaperPMID 39572163Full record

SynthesisRenal failure2024

Global trends and prospects related to macrophage in chronic kidney disease: a bibliometric analysis.

Yuxin Hu, Yaoxian Wang, Hanzhang Hong, Yexin Chen, Qinjie Zhou, Gegongming Zhu, Jingyi Tang, Weijing Liu, Lin Wang

Abstract readSystematic Review
In one paragraph

Synthesis in Renal failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuxin HuDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Yaoxian WangDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Hanzhang HongBeijing University of Chinese Medicine, Beijing, China.
Yexin ChenDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Qinjie ZhouDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Gegongming ZhuBeijing University of Chinese Medicine, Beijing, China.
Jingyi TangDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Weijing LiuDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.
Lin WangDongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsMacrophages play a variety of widely concerned roles in the process of chronic kidney disease (CKD). To further understand the research hotspots and development trends regarding the relationship between macrophages and CKD, the role of macrophages in the occurrence and progression of CKD was summarized by bibliometrics in this study. MATERIAL AND

methodsWe collected the studies relevant the role of macrophages in CKD from the Web of Science Core Collection, which included 1332 relevant studies from Jan 1st, 2004 to Jul 6th, 2023 in WoSCC. CiteSpace, biblioshiny in R, VOSviewer and SCImago Graphica Beta were used for bibliometric analysis and visualization.

resultsMonash University from Australia is the most productive institution, while China and the USA are most productive countries. Anders HJ is the most cited author. In terms of the number of co-citations, the top one was "Macrophages: versatile players in renal inflammation and fibrosis" by Patrick Ming-Kuen Tang, published in Nature Reviews Nephrology in 2019. Important keywords of this research topic include inflammation, dendritic cell, oxidative stress, NF-κB, tgf-beta, interstitial fibrosis, glomerulonephritis, diabetic nephropathy. Future research hotspots may include molecular mechanism, acute kidney injury, macrophage polarization, kidney fibrosis.

conclusionThis study provides a systematic review of the role of macrophages in CKD and speculates that future research hotspots. Previous studies have focused on the immune function of macrophages and atypia, and metabolic factors (especially iron metabolism within macrophages) have attracted the attention of researchers in recent years and are the forefront of recent research.

Indexed as

BibliometricsMacrophagesRenal Insufficiency, ChronicFibrosisHumansbibliometric analysisChronic kidney diseasediabetic nephropathyfibrosismacrophagemetabolic syndrome

Identifiers

PMID39572163
PMCPMC11583328

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.