Evidence map›Paper›PMID 39573878›Full record

ArticleBiophysical journal2025

GPVI-mediated thrombus stabilization of shear-induced platelet aggregates in a microfluidic stenosis.

Connor T Watson, Christopher A Siedlecki, Keefe B Manning

Abstract read
In one paragraph

Article in Biophysical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Connor T WatsonDepartment of Biomedical Engineering, The Pennsylvania State University, University Park, Pennsylvania.
Christopher A SiedleckiDepartment of Biomedical Engineering, The Pennsylvania State University, University Park, Pennsylvania; Department of Surgery, Penn State College of Medicine, Hershey, Pennsylvania.
Keefe B ManningDepartment of Biomedical Engineering, The Pennsylvania State University, University Park, Pennsylvania; Department of Surgery, Penn State College of Medicine, Hershey, Pennsylvania. Electronic address: kbm10@psu.edu.

Funding

Penn State Clinical and Translational Science InstituteUL1TR002014 · NCATS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KRASCHNEWSKI, JENNIFER L. · 2016 to 2025
$33.7M
A Structured Approach to the Design of Minimally Traumatic Blood PumpsR01HL136369 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI CYSYK, JOSHUA P, MANNING, KEEFE B · 2018 to 2021
$2.6M
NCATS NIH HHS UL1 TR002014NHLBI NIH HHS R01 HL136369
6 · The paper itself

Abstract

Supraphysiological shear rates (>2000 s

Indexed as

Platelet AggregationPlatelet Membrane GlycoproteinsThrombosisBlood PlateletsConstriction, PathologicHumansShear StrengthPlatelet Membrane Glycoproteinsplatelet membrane glycoprotein VI

Identifiers

PMID39573878
PMCPMC11739887

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.