Evidence map›Paper›PMID 39574576›Full record

ArticlebioRxiv : the preprint server for biology2024

Direct lipid interactions control SARS-CoV-2 M protein conformational dynamics and virus assembly.

Mandira Dutta, Kimberly A Dolan, Souad Amiar, Elijah J Bass, Rokaia Sultana, Gregory A Voth, Stephen G Brohawn, Robert V Stahelin

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Mandira DuttaDepartment of Chemistry, The University of Chicago, Chicago, IL 60637.
Kimberly A DolanDepartment of Molecular & Cell Biology, Department of Neuroscience, California Institute for Quantitative Biology (QB3), Biophysics Graduate Program, University of California Berkeley, Berkeley, California 94720, USA.
Souad AmiarBorch Department of Medicinal Chemistry and Molecular Pharmacology and the Purdue Institute of Inflammation, Immunology and Infectious Disease, Purdue University, West Lafayette, Indiana 47907.
Elijah J BassBorch Department of Medicinal Chemistry and Molecular Pharmacology and the Purdue Institute of Inflammation, Immunology and Infectious Disease, Purdue University, West Lafayette, Indiana 47907.
Rokaia SultanaBorch Department of Medicinal Chemistry and Molecular Pharmacology and the Purdue Institute of Inflammation, Immunology and Infectious Disease, Purdue University, West Lafayette, Indiana 47907.
Gregory A VothDepartment of Chemistry, The University of Chicago, Chicago, IL 60637.
Stephen G BrohawnDepartment of Molecular & Cell Biology, Department of Neuroscience, California Institute for Quantitative Biology (QB3), Biophysics Graduate Program, University of California Berkeley, Berkeley, California 94720, USA.ORCID 0000-0001-6768-3406
Robert V StahelinBorch Department of Medicinal Chemistry and Molecular Pharmacology and the Purdue Institute of Inflammation, Immunology and Infectious Disease, Purdue University, West Lafayette, Indiana 47907.

Funding

Elucidation of Assembly and Budding Mechanisms of SARS-CoV-2R01AI169896 · NIAID · PURDUE UNIVERSITY · PI Robert Virgil Stahelin · 2022 to 2026
$3.8M
NIAID NIH HHS R01 AI169896
6 · The paper itself

Abstract

M is the most abundant structural membrane protein in coronaviruses and is essential for the formation of infectious virus particles. SARS-CoV-2 M adopts two conformations, M

Identifiers

PMID39574576
PMCPMC11580925

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.