Evidence map›Paper›PMID 39574635›Full record

ArticlebioRxiv : the preprint server for biology2024

Axonal spheroids are regulated by Schwann cells after peripheral nerve injury.

Sarah Hunter-Chang, Charlene Kim-Aun, Heeran Karim, Marieke Jones, Tanvika Vegiraju, Ekaterina Stepanova, Brynn Manke, Sarah Kucenas, Christopher Deppmann

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sarah Hunter-ChangDepartment of Biology, University of Virginia, 485 McCormick Road, P.O. Box 400328, Charlottesville, VA, 22904-4328, USA.ORCID 0000-0003-2309-8939
Charlene Kim-AunDepartment of Biology, University of Virginia, 485 McCormick Road, P.O. Box 400328, Charlottesville, VA, 22904-4328, USA.
Heeran KarimDepartment of Biology, University of Virginia, 485 McCormick Road, P.O. Box 400328, Charlottesville, VA, 22904-4328, USA.
Marieke JonesDepartment of Public Health Sciences, University of Virginia, 200 Jeanette Lancaster Way, Charlottesville, VA, 22904-4328, USA.ORCID 0000-0001-5045-6725
Tanvika VegirajuDepartment of Biology, University of Virginia, 485 McCormick Road, P.O. Box 400328, Charlottesville, VA, 22904-4328, USA.
Ekaterina StepanovaDepartment of Biology, University of Virginia, 485 McCormick Road, P.O. Box 400328, Charlottesville, VA, 22904-4328, USA.ORCID 0000-0002-1977-9785
Brynn MankeDepartment of Biology, University of Virginia, 485 McCormick Road, P.O. Box 400328, Charlottesville, VA, 22904-4328, USA.
Sarah KucenasDepartment of Biology, University of Virginia, 485 McCormick Road, P.O. Box 400328, Charlottesville, VA, 22904-4328, USA.ORCID 0000-0002-1950-751X
Christopher DeppmannDepartment of Biology, University of Virginia, 485 McCormick Road, P.O. Box 400328, Charlottesville, VA, 22904-4328, USA.ORCID 0000-0002-6591-1767

Funding

Extrinsic Mechanisms Governing Injury-Induced Axon DegenerationR01NS091617 · NINDS · UNIVERSITY OF VIRGINIA · PI DEPPMANN, CHRISTOPHER D · 2015 to 2025
$4.0M
Characterization of the cellular and molecular mechanisms that mediate glial tilingR01NS107525 · NINDS · UNIVERSITY OF VIRGINIA · PI KUCENAS, SARAH C · 2019 to 2023
$1.7M
Elucidating glial diversity in the peripheral nervous systemR21NS124164 · NINDS · UNIVERSITY OF VIRGINIA · PI KUCENAS, SARAH C · 2021 to 2021
$444k
NINDS NIH HHS R01 NS091617NINDS NIH HHS R01 NS107525NINDS NIH HHS R21 NS124164
6 · The paper itself

Abstract

Axonal spheroids are hallmark features of neurodegeneration, forming along degenerating axons and contributing to disease progression. Despite their ubiquity across degenerative etiologies, the dynamics of spheroid disappearance, as well as their interactions with glial cells, remain poorly understood. Here, using an

Identifiers

PMID39574635
PMCPMC11581001

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.