ArticlebioRxiv : the preprint server for biology2024
DNA repair and anti-cancer mechanisms in the long-lived bowhead whale.
Abstract readPreprint
In one paragraph
Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Peto's paradox's relevance is off the scale.Aging · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
52 authors.
Denis FirsanovDepartment of Biology, University of Rochester, Rochester, NY, USA.ORCID 0000-0003-1573-0113
Max ZacherDepartment of Biology, University of Rochester, Rochester, NY, USA.ORCID 0000-0003-0377-7221
Xiao TianDepartment of Biology, University of Rochester, Rochester, NY, USA.ORCID 0000-0001-5300-3596
Todd L SformoDepartment of Wildlife Management, North Slope Borough, Utqiaġvik (Barrow), AK 99723, USA.ORCID 0000-0003-4833-2007
Yang ZhaoDepartment of Biology, University of Rochester, Rochester, NY, USA.
Greg TomblineDepartment of Biology, University of Rochester, Rochester, NY, USA.
J Yuyang LuDepartment of Biology, University of Rochester, Rochester, NY, USA.
Zhizhong ZhengDepartment of Biology, University of Rochester, Rochester, NY, USA.
Luigi PerelliDepartment of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Enrico GurreriDepartment of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Li ZhangDepartment of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jing GuoDepartment of Biology, University of Rochester, Rochester, NY, USA.
Anatoly KorotkovDepartment of Biology, University of Rochester, Rochester, NY, USA.
Valentin VolobaevDepartment of Biology, University of Rochester, Rochester, NY, USA.
Seyed Ali BiashadDepartment of Biology, University of Rochester, Rochester, NY, USA.ORCID 0000-0001-9591-7687
Zhihui ZhangDepartment of Biology, University of Rochester, Rochester, NY, USA.
Johanna HeidDepartment of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Alex MaslovDepartment of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Shixiang SunDepartment of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Zhuoer WuDepartment of Biology, University of Rochester, Rochester, NY, USA.
Jonathan GigasDepartment of Biology, University of Rochester, Rochester, NY, USA.
Eric HillpotDepartment of Biology, University of Rochester, Rochester, NY, USA.
John MartinezDepartment of Biology, University of Rochester, Rochester, NY, USA.
Minseon LeeDepartment of Biology, University of Rochester, Rochester, NY, USA.
Alyssa WilliamsDepartment of Biology, University of Rochester, Rochester, NY, USA.
Abbey GilmanDepartment of Biology, University of Rochester, Rochester, NY, USA.
Nicholas HamiltonDepartment of Biology, University of Rochester, Rochester, NY, USA.
Ena HaseljicDepartment of Biology, University of Rochester, Rochester, NY, USA.
Avnee PatelDepartment of Biology, University of Rochester, Rochester, NY, USA.
Maggie StraightDepartment of Biology, University of Rochester, Rochester, NY, USA.
Nalani MillerDepartment of Biology, University of Rochester, Rochester, NY, USA.
Julia AblaevaDepartment of Biology, University of Rochester, Rochester, NY, USA.
Lok Ming TamDepartment of Biology, University of Rochester, Rochester, NY, USA.
Chloé CoudercDepartment of Biology, University of Rochester, Rochester, NY, USA.
Michael HoopmanInstitute for Systems Biology, Seattle, WA USA.
Robert MoritzInstitute for Systems Biology, Seattle, WA USA.
Shingo FujiiCancer Research Center of Marseille, Department of Genome Integrity, CNRS UMR7258, Inserm U1068, Institut Paoli-Calmettes, Aix Marseille Univ, Marseille, France.
Dan J HaymanSchool of Biosciences, University of Sheffield, UK.
Hongrui LiuDepartment of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Yuxuan CaiDepartment of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Anthony K L LeungDepartment of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Mirre J P SimonsSchool of Biosciences, University of Sheffield, UK.
Zhengdong ZhangDepartment of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0000-0001-9508-1429
C Bradley NelsonHuntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Lisa M AbegglenDepartment of Pediatrics & Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Joshua D SchiffmanDepartment of Pediatrics & Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.
Vadim N GladyshevDivision of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-0372-7016
Mauro ModestiCancer Research Center of Marseille, Department of Genome Integrity, CNRS UMR7258, Inserm U1068, Institut Paoli-Calmettes, Aix Marseille Univ, Marseille, France.
Giannicola GenoveseDepartment of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jan VijgDepartment of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0000-0002-8457-9595
Andrei SeluanovDepartment of Biology, University of Rochester, Rochester, NY, USA.ORCID 0000-0003-3400-538X
Vera GorbunovaDepartment of Biology, University of Rochester, Rochester, NY, USA.ORCID 0000-0001-8979-0333
Funding
The role of hyaluronan in longevity and cancer resistance of longest-lived rodentP01AG047200 · NIA · UNIVERSITY OF ROCHESTER · PI Vadim N. Gladyshev · 2014 to 2026
$36.9MSomatic Activation of Retrotransposition: A New Molecular Mechanism of Aging?P01AG051449 · NIA · BROWN UNIVERSITY · PI John M Sedivy · 2016 to 2026
$30.4MThe role of SIRT6 posttranslational modifications in aging and genome stability. Supplement: Testing SIRT6 activators as potential Alzheimer's disease therapy.R01AG027237 · NIA · UNIVERSITY OF ROCHESTER · PI Vera Gorbunova · 2006 to 2026
$6.2MRegulation of epigenome stability by SIRT6 during aging. Supplement: Does centenarian variant of SIRT6 or bowhead whale SIRT6 confer protection from Alzheimer's disease?R37AG046320 · NIA · UNIVERSITY OF ROCHESTER · PI Andrei Seluanov · 2019 to 2026
$4.7MRole of ADP-Ribosylation in Stress Granules-Equipment SupplementR01GM104135 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Anthony K L Leung · 2015 to 2026
$4.2MRegulation of genome stability by SITR6R01AG046320 · NIA · UNIVERSITY OF ROCHESTER · PI SELUANOV, ANDREI · 2014 to 2018
$1.9MSTED3X Super Resolution Microscope for The University of Rochester and Western NY research communityS10OD023440 · OD · UNIVERSITY OF ROCHESTER · PI YULE, DAVID I · 2018 to 2018
$600kNIA NIH HHS P01 AG047200NIA NIH HHS P01 AG051449NIA NIH HHS R01 AG027237NIA NIH HHS R01 AG046320NIA NIH HHS R37 AG046320NIGMS NIH HHS R01 GM104135NIH HHS S10 OD023440
Abstract
At over 200 years, the maximum lifespan of the bowhead whale exceeds that of all other mammals. The bowhead is also the second-largest animal on Earth, reaching over 80,000 kg
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What Socratic holds
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LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.