Evidence map›Paper›PMID 39574950›Full record

Trial reportFrontiers in endocrinology2024

Comparative study on pregnancy complications: PGT-A vs. IVF-ET with gender-specific outcomes.

Ling Guo, Xiao Li, Anliang Guo, Yufeng Wang, Yue Liang, Yan Li, Xinbo Xu, Hong Lv

Registry-linked trialAbstract readComparative StudyMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Frontiers in endocrinology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03118141 (Cumulative Live Birth Rate With eSET After In-vitro Fertilization With Preim-plantation Genetic Screening by Next Generation Sequencing Versus Conventional In-vitro Fertilization), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03118141 naunknown statusnot on this map

Cumulative Live Birth Rate With eSET After In-vitro Fertilization With Preim-plantation Genetic Screening by Next Generation Sequencing Versus Conventional In-vitro Fertilization: A Pragmatic Randomized Controlled Clinical Trial

TypeinterventionalSponsorChen Zi-JiangRan2017 to 2020Enrolled1,215ConditionsInfertilityArmsblastocyst morphologic score, blastocyst biopsy and sequencing, freeze-all and single thawed blastocyst transfer
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ling Guo *Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Xiao Li *Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Anliang Guo *Department of Obstetrics and Gynecology, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Yufeng WangMedical Integration and Practice Center, Shandong University, Jinan, Shandong, China.
Yue LiangMedical Integration and Practice Center, Shandong University, Jinan, Shandong, China.
Yan LiMedical Integration and Practice Center, Shandong University, Jinan, Shandong, China.
Xinbo XuDepartment of Otolaryngology, Qilu Hospital of Shandong University, Jinan, Shandong, China.
Hong LvMedical Integration and Practice Center, Shandong University, Jinan, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The safety and clinical effectiveness of preimplantation genetic testing for aneuploidy (PGT-A) in improving pregnancy outcomes for sub-fertile patients remains controversial. Potential sex-based differences in the relationship between PGT-A and pregnancy complications have not been investigated, which could guide the appropriate clinical application of PGT-A. In this secondary analysis of data from a multicenter, randomized, controlled, non-inferiority trial (NCT03118141), 940 women who achieved singleton live birth during the trial were included to estimate the between-group differences in pregnancy complications following PGT-A versus conventional

Indexed as

Fertilization in VitroPregnancy ComplicationsPregnancy OutcomePreimplantation DiagnosisAdultAneuploidyEmbryo TransferFemaleGenetic TestingHumansMalePre-EclampsiaPregnancySex Factorsfetal sexin vitro fertilization and embryo transferpreeclampsiapreimplantation genetic testing for aneuploidysingleton pregnancy

Identifiers

PMID39574950
PMCPMC11579861

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.