Evidence map›Paper›PMID 39575479›Full record

ReviewOncology reports2025

Exosome applications for the diagnosis and treatment of pancreatic ductal adenocarcinoma: An update (Review).

Xinchi Luan, Xuezhe Wang, Gang Bian, Xiaoxuan Li, Ziru Gao, Zijiao Liu, Zhishang Zhang, Tianyue Han, Jinpeng Zhao, Hongjiao Zhao and 4 more

Abstract readReview
In one paragraph

Review in Oncology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Xinchi Luan *Pathophysiology Department, School of Basic Medicine, Qingdao University, Qingdao, Shandong 266071, P.R China.
Xuezhe Wang *Pathophysiology Department, School of Basic Medicine, Qingdao University, Qingdao, Shandong 266071, P.R China.
Gang BianDepartment of Gastroenterology, Affiliated Qingdao Third People's Hospital, Qingdao University, Qingdao, Shandong 266041, P.R. China.
Xiaoxuan LiDepartment of Oncology, Key Laboratory of Cancer Molecular and Translational Research, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266031, P.R. China.
Ziru GaoPathophysiology Department, School of Basic Medicine, Qingdao University, Qingdao, Shandong 266071, P.R China.
Zijiao LiuSchool of Clinical and Basic Medicine and Institute of Basic Medicine, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong 250117, P.R. China.
Zhishang ZhangPathophysiology Department, School of Basic Medicine, Qingdao University, Qingdao, Shandong 266071, P.R China.
Tianyue HanPathophysiology Department, School of Basic Medicine, Qingdao University, Qingdao, Shandong 266071, P.R China.
Jinpeng ZhaoPathophysiology Department, School of Basic Medicine, Qingdao University, Qingdao, Shandong 266071, P.R China.
Hongjiao ZhaoPathophysiology Department, School of Basic Medicine, Qingdao University, Qingdao, Shandong 266071, P.R China.
Xinyue LuanPathophysiology Department, School of Basic Medicine, Qingdao University, Qingdao, Shandong 266071, P.R China.
Wuhui ZhuDepartment of Hepatobiliary surgery, Affiliated Qingdao Third People's Hospital, Qingdao University, Qingdao, Shandong 266041, P.R. China.
Lili DongDepartment of Gastroenterology, Affiliated Qingdao Third People's Hospital, Qingdao University, Qingdao, Shandong 266041, P.R. China.
Feifei GuoPathophysiology Department, School of Basic Medicine, Qingdao University, Qingdao, Shandong 266071, P.R China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is a malignant neoplasm that typically manifests with subtle clinical manifestations in its early stages and frequently eludes diagnosis until the advanced phases of the disease. The limited therapeutic options available for PDAC significantly contribute to its high mortality rate, highlighting the urgent need for novel biomarkers capable of effectively identifying early clinical manifestations and facilitating precise diagnosis. The pivotal role of cellular exosomes in both the pathogenesis and therapeutic interventions for PDAC has been underscored. Furthermore, researchers have acknowledged the potential of exosomes as targeted drug carriers against regulatory cells in treating PDAC. The present article aims to provide a comprehensive review encompassing recent advancements in utilizing exosomes for elucidating mechanisms underlying disease development, patterns of metastasis, diagnostic techniques and treatment strategies associated with PDAC.

Indexed as

Biomarkers, TumorCarcinoma, Pancreatic DuctalExosomesPancreatic NeoplasmsHumansBiomarkers, TumorbiomarkerdiagnosisexosomePDACtreatment

Identifiers

PMID39575479
PMCPMC11605277

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.