Evidence map›Paper›PMID 39575862›Full record

ArticleActa paediatrica (Oslo, Norway : 1992)2025

Lung function outcomes in adults born extremely preterm across three decades of advancing perinatal medicine.

Tonje Bårdsen, Emma Satrell, Ola Drange Røksund, Merete Røineland Benestad, Karl Ove Hufthammer, Hege Clemm, Ingvild Bruun Mikalsen, Knut Øymar, Thomas Halvorsen, Maria Vollsæter

Abstract read
In one paragraph

Article in Acta paediatrica (Oslo, Norway : 1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Bronchopulmonary dysplasia and extremely preterm birth: time for a broader perspective on long-term outcomes.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tonje BårdsenDepartment of Paediatric and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0001-9518-5463
Emma SatrellDepartment of Paediatric and Adolescent medicine, Oslo University Hospital, Oslo, Norway.ORCID 0000-0002-9172-8608
Ola Drange RøksundDepartment of Paediatric and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0002-8381-0142
Merete Røineland BenestadDepartment of Paediatric and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0002-0726-1700
Karl Ove HufthammerCentre for Clinical Research, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0003-3170-9496
Hege ClemmDepartment of Paediatric and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0002-0096-4032
Ingvild Bruun MikalsenDepartment of Clinical Science, University of Bergen, Bergen, Norway.ORCID 0000-0003-4192-8342
Knut ØymarDepartment of Clinical Science, University of Bergen, Bergen, Norway.ORCID 0000-0003-2656-9652
Thomas HalvorsenDepartment of Paediatric and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0003-1471-0225
Maria VollsæterDepartment of Paediatric and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway.ORCID 0000-0003-2545-0190

Funding

Helse Vest F-12516The Western Norway Regional Health Authority
6 · The paper itself

Abstract

aimAdvances in perinatal medicine from 1980 to 2000 improved survival in extremely preterm (EP) neonates. Long-term effects of these developments remain unclear, and we aimed to investigate potential cohort effects on adult lung function.

methodsThree 18-year-old population-based cohorts born at ≤28 weeks gestation or with birthweight ≤1000 g during 1982-85, 1991-92 and 1999-2000 and term-controls underwent spirometry, body plethysmography, and tests of lung diffusing capacity, bronchodilator reversibility, and airway hyperresponsiveness. We used Welch's t-tests to compare term- with EP-born as a group and split by bronchopulmonary dysplasia (BPD), and regression models to test group/cohort interactions.

resultsIn all EP-born cohorts, z-scores for FEV

conclusionAdults born EP across three formative decades of neonatal care had stable lung function overall, with notable improvements in BPD subgroups across cohorts.

Indexed as

Infant, Extremely PrematureLungAdolescentBronchopulmonary DysplasiaCohort StudiesFemaleHumansInfant, NewbornMaleRespiratory Function TestsadultBPDcohort studyextremely prematurerespiratory outcome

Identifiers

PMID39575862
PMCPMC11976140

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.