Evidence map›Paper›PMID 39576115›Full record

ArticlemBio2025

An inner membrane complex protein IMC1g in

Yinjie Liu, Shitong Cheng, Gang He, Dawei He, Duo Wang, Sicong Wang, Lumeng Chen, Liying Zhu, Yonghui Feng, Liwang Cui and 2 more

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. mBio · 2025
    Article
  5. Malaria: past, present, and future.Signal transduction and targeted therapy · 2025
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yinjie Liu *Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, China.
Shitong Cheng *Department of Laboratory Medicine, the First Hospital of China Medical University, Shenyang, Liaoning, China.
Gang He *Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, China.
Dawei HeDepartment of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, China.
Duo WangDepartment of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, China.
Sicong WangDepartment of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, China.
Lumeng ChenDepartment of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, China.
Liying ZhuDepartment of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, China.
Yonghui FengDepartment of Laboratory Medicine, the First Hospital of China Medical University, Shenyang, Liaoning, China.ORCID 0000-0003-3145-6409
Liwang CuiDepartment of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.ORCID 0000-0002-8338-1974
Yaming Cao *Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, China.ORCID 0000-0001-5315-1636
Xiaotong Zhu *Department of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, China.ORCID 0000-0002-9064-586X

Funding

Southeast Asia Malaria Research CenterU19AI089672 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI CUI, LIWANG · 2010 to 2023
$28.9M
Molecular Mechanisms of Artemisinin ResistanceR01AI128940 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI CUI, LIWANG · 2017 to 2021
$971k
Antigen discovery for transmission-blocking vaccines in Plasmodium vivaxR01AI150533 · NIAID · CHINA MEDICAL UNIVERSITY · PI CAO, YAMING · 2020 to 2024
$677k
Department of Science and Technology of Liaoning Province () 2022-MS-239HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI128940HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) U19AI089672MOST | National Natural Science Foundation of China (NSFC) 82372280NIAID NIH HHS R01 AI128940NIAID NIH HHS R01 AI150533NIAID NIH HHS U19 AI089672
6 · The paper itself

Abstract

The inner membrane complex (IMC), a double-membrane organelle underneath the plasma membrane in apicomplexan parasites, plays a significant role in motility and invasion and confers shape to the cell. We characterized the function of PbIMC1g, a component of the IMC1 family member in IMPORTANCE: The malaria parasite's inner membrane complex is critical to maintain its structural integrity and motility. Here, we identified the function of the IMC1g protein, a member of the IMC1 family, in invasive and proliferative stages of

Indexed as

MalariaPlasmodium bergheiProtozoan ProteinsAnimalsFemaleMaleMembrane ProteinsMiceTwo-Hybrid System TechniquesMembrane ProteinsProtozoan Proteinsgliding motilityIMC1inner membrane complexmalariaPlasmodium berghei

Identifiers

PMID39576115
PMCPMC11708024

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.