ArticleScience advances2024
Enhanced dual-mode imaging: Superior photoacoustic and ultrasound endoscopy in live pigs using a transparent ultrasound transducer.
Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed.
- Photoacoustic and ultrasound Imaging of placental functions in gestational diabetes: From diagnosis to precision interventions.Photoacoustics · 2026Review
- From lab design to clinical translation: photoacoustic endoscopy.Photoacoustics · 2026Review
- A Low-Cost, Lightweight High-Frequency Ultrasound Transducer with Aluminum Electrodes and 3D-Printed Polymer Housing.Biosensors · 2026Article
- Applications and challenges of photoacoustic technology in internal medicine.Journal of translational internal medicine · 2026Article
- Robust hybrid feature-driven on-the-fly mapping enables freehand 3D panoramic photoacoustic angiography.Light, science & applications · 2026Article
- Activatable smart contrast agents for photoacoustic imaging.Smart molecules : open access · 2026Review
- Multiscale photoacoustic imaging of stroke in preclinical models and future directions toward clinical translation [Invited].Biomedical optics express · 2026Review
- All-fiber photoacoustic endomicroscopy reveals layer-specific angiogenesis-oxygenation uncoupling in experimental colitis.Science advances · 2026Article
- Fabrication of optically transparent ultrasound transducers to integrate light and sound in multimodal biomedical systems.Nature protocols · 2026Review
- Fully integrated photoacoustic microscopy for multi-scale and longitudinal imaging in translational biomedical applications.Biomedical optics express · 2026Article
- Photoacoustic Imaging for Women's Gynecological Health: Advances and Clinical Prospects.Bioengineering (Basel, Switzerland) · 2026Review
- Volumetric photoacoustic/ultrasound image fusion and enhancement with dual-tree complex wavelet transform.Biomedical optics express · 2026Article
- Advances and Opportunities in NIR-II Endoscopy: From Diagnosis to Therapeutic Applications.Diagnostics (Basel, Switzerland) · 2026Review
- Ionizing radiation acoustic beam localization: one step towards "proton surgery".medRxiv : the preprint server for health sciences · 2026Article
- Fusing photoacoustic microscopy and ultrasound imaging: an artificial intelligence strategy for vessel enhancement in interventional guidance.Biomedical optics express · 2026Article
- Circular-scanning variance delay and sum algorithm for photoacoustic imaging.Biomedical optics express · 2026Article
- Tethered optoacoustic and optical coherence tomography capsule endoscopy for label-free assessment of Barrett's oesophageal neoplasia.Nature biomedical engineering · 2026Article
- From light to sound: Seeing and hearing the placenta in health and disease.Science advances · 2026Review
- Three-Dimensional Reconstruction and Navigation Systems in Endoscopic Ultrasound Procedures: A Comprehensive Review.Diagnostics (Basel, Switzerland) · 2026Review
- Label-free mid-infrared dichroism-sensitive photoacoustic microscopy for histostructural analysis of engineered heart tissues.Light, science & applications · 2026Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dual-mode photoacoustic/ultrasound endoscopy (ePAUS) is a promising tool for preclinical and clinical interventions. To be clinically useful, ePAUS must deliver high-performance ultrasound imaging comparable to commercial systems and maintain high photoacoustic imaging performance at long working distances. This requires a transducer with an intact physical aperture and coaxial alignment of acoustic and optical beams within the probe, a challenging integration task. We present a high-performance ePAUS probe with a miniaturized, optically transparent ultrasonic transducer (TUT) called ePAUS-TUT. The 1.8-mm-diameter probe, fitting into standard endoscopic channels, aligns acoustic and optical beams efficiently, achieving commercial-level ultrasound and high-resolution photoacoustic imaging over long distances. These imaging capabilities were validated through in vivo imaging of a rat's rectum and a pig's esophagus. The ePAUS-TUT system substantially enhances feasibility and potential for clinical applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.