Evidence mapPaperPMID 39578110Full record

ReviewSeminars in nuclear medicine2025

Role of Total Body PET/CT in Inflammatory Disorders.

Shervin Zoghi, Clemens Mingels, Ramsey D Badawi, Benjamin A Spencer, Tracy L Yarbrough, Lorenzo Nardo, Abhijit J Chaudhari

Abstract readReview
In one paragraph

Review in Seminars in nuclear medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. A scoping review on potential of novel developments in fever of unknown origin and inflammation of unknown origin: long-axial-field-of-view positron emission tomography/computed tomography and novel radiotracers.The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... · 2025
    Article
  6. CD45-targeted PET enables the visualization of inflammatory conditions.American journal of nuclear medicine and molecular imaging · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shervin ZoghiDepartment of Radiology, University of California Davis, Sacramento, CA, USA. Electronic address: szoghi@ucdavis.edu.
Clemens MingelsDepartment of Radiology, University of California Davis, Sacramento, CA, USA; Department of Nuclear Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Ramsey D BadawiDepartment of Radiology, University of California Davis, Sacramento, CA, USA.
Benjamin A SpencerDepartment of Radiology, University of California Davis, Sacramento, CA, USA.
Tracy L YarbroughDepartment of Radiology, University of California Davis, Sacramento, CA, USA.
Lorenzo NardoDepartment of Radiology, University of California Davis, Sacramento, CA, USA.
Abhijit J ChaudhariDepartment of Radiology, University of California Davis, Sacramento, CA, USA.

Funding

Characterization of Spinal Pathology in Axial Psoriatic ArthritisR01AR085314 · UNIVERSITY OF CALIFORNIA AT DAVIS · 2025 to 2025
$239k
NCCIH NIH HHS R61 AT012187NCI NIH HHS R01 CA206187NIAMS NIH HHS R01 AR076088NIAMS NIH HHS R01 AR085314NIH HHS S10 OD030440
6 · The paper itself

Abstract

Inflammatory disorders historically have been difficult to monitor with conventional PET imaging due to limitations including radiation exposure, lack of validated imaging biomarkers, low spatial resolution, and long acquisition durations. However, the recent development of long-axial field-of-view (LAFOV) PET/CT scanners may allow utilization of novel noninvasive biomarkers to diagnose, predict outcomes, and monitor therapeutic response of inflammatory conditions. LAFOV PET scanners can image most of the human body (if not the entire body) simultaneously in one bed position, with improved signal collection efficiency compared to conventional PET scanners. This allows for imaging with shorter acquisition durations, decreased injected radiotracer dose, prolonged uptake times, or a combination of any of these. In addition, LAFOV PET scanners enable whole-body dynamic imaging. Altogether, these intrinsically superior capabilities in assessing both local and systemic diseases, have allowed these scanners to make increasingly significant contributions to the assessment of inflammatory conditions. This review aims to further explore the role and benefits of LAFOV scanners for imaging various inflammatory conditions while addressing future developments and challenges faced by this technology.

Indexed as

InflammationPositron Emission Tomography Computed TomographyWhole Body ImagingHumans

Identifiers

PMID39578110
PMCPMC11645246

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.