Evidence map›Paper›PMID 39578776›Full record

ArticleBMC infectious diseases2024

Fecal carriage of extended-spectrum β-lactamase-producing, and carbapenem-resistant gram-negative bacteria among hemodialysis patients in a palestinian tertiary care hospital.

Abdullah Janem, Dawod Jawabreh, Yaqoot Anabseh, Mohammed Jawabreh, Zaher Nazzal, Adham Abu Taha, Mohammad Qadi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Abdullah Janem *Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 4439, State of Palestine.
Dawod Jawabreh *Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 4439, State of Palestine.
Yaqoot Anabseh *Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 4439, State of Palestine.
Mohammed JawabrehDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, State of Palestine.
Zaher NazzalDepartment of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 4439, State of Palestine.
Adham Abu TahaDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, State of Palestine. aabutaha@najah.edu.
Mohammad QadiDepartment of Biomedical Sciences, Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, State of Palestine. m.qadi@najah.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study explores the presence of extended-spectrum β-lactamase-producing Gram-negative bacteria (ESBL-GNB) and carbapenem-resistant Gram-negative bacteria (CR-GNB) in the stool of hemodialysis patients, reflecting a significant concern amid rising antibiotic resistance. This cross-sectional study included 137 outpatients conducted from October to December 2023 at An-Najah National University Hospital. Samples were incubated on appropriate MacConkey-based agar for bacterial analysis, and potential risk factors were evaluated using logistic regression. Out of 137 stool samples, 116 (84.7%) were positive for ESBL-producing bacteria, and 8 (5.8%) for carbapenem-resistant bacteria. Age of the patients (aOR: 1.068; p: 0.012), hypertension (aOR: 15.582; p: 0.0107), ischemic heart disease (aOR: 5.381; p: 0.040), the timing of the dialysis shift (aOR: 8.864; p: 0,005), and the level of blood urea nitrogen (aOR: 1.049; p: 0.045) were independently associated with ESBL-GNB colonization. Carbapenem-resistant bacteria colonization presented an inverse association with ischemic heart disease (aOR: 0.052; p: 0.041). This study highlights a significant prevalence of ESBL-GNB colonization linked with age and comorbidities such as hypertension. An inverse association of CR-GNB colonization with ischemic heart disease was observed, suggesting a complex interplay between patient health status and antibiotic-resistant bacterial colonization.

Indexed as

beta-LactamasesCarbapenem-Resistant EnterobacteriaceaeCarrier StateEnterobacteriaceae InfectionsFecesRenal DialysisAgedCross-Sectional StudiesFemaleHumansHypertensionMaleMiddle AgedMiddle EastMyocardial IschemiaRisk Factorsbeta-LactamasesAntimicrobial resistanceCarbapenem-resistantExtended-spectrum β-lactamaseFecal colonizationFecal indicator bacteriaHemodialysisTransmissible infectionsTransmitted drug resistance

Identifiers

PMID39578776
PMCPMC11583790

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.