SynthesisCellular and molecular neurobiology2024
The Role of Photobiomodulation to Modulate Ion Channels in the Nervous System: A Systematic Review.
Synthesis in Cellular and molecular neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Pulsed 830-nm Laser Irradiation Modulates Aδ- and C-Fiber-Mediated Pain Thresholds in Healthy Adults: A Randomized, Sham-Controlled Trial.Lasers in surgery and medicine · 2026Trial
- A Translational Review of Mechanisms of Effectiveness of Photobiomodulation on Somatosensory Neurons and the Peripheral Nervous System-From Molecular Mechanisms to Clinical Applications in Medicine and Dentistry.Current issues in molecular biology · 2026Review
- Integration of Three-Dimensional Cell Culture Techniques and Photobiomodulation for Supportive Differentiation of Adipose-Derived Stem Cells into Smooth Muscle.Cell biochemistry and function · 2026Review
- Review
- Low-Level Light Therapy in Postherpetic Neuralgia: A Review of Mechanistic Insights and Clinical Implications.Cellular and molecular neurobiology · 2026Review
- Optogenetic Strategies for Motor Recovery After Ischemic Stroke: Mechanisms and Therapeutic Implications.Cellular and molecular neurobiology · 2026Review
- Article
- Effects of a Nanotechnology-Based Application on Balance Control in Hearing Aid Users.Audiology research · 2026Article
- Exploring Photobiomodulation as a Potential Novel Intervention for Developmental Stuttering: A Review and Hypothesis.Journal of clinical medicine · 2026Review
- Photobiomodulation and Addiction: Exploring Mechanisms, Therapeutic Potential, and Future Directions in Substance Use Disorders.Neuroscience bulletin · 2026Article
- Photobiomodulation as an adjuvant for pain relief and healing pre-orthodontic mandibular third molar surgery: double-blinded randomized clinical trial.The Saudi dental journal · 2026Article
- Article
- The effect of photobiomodulation therapy on neurosensory recovery of infra-alveolar nerve following iatrogenic trauma: A literature review.Journal of dental sciences · 2026Article
- Non-invasive brain stimulation in frontotemporal dementia: syndrome-specific signals and priorities for future trials.Frontiers in aging neuroscience · 2026Review
- Application of photobiomodulation in post-stroke dysfunctions: a literature review of recent clinical studies.Frontiers in neurology · 2026Review
- Photobiomodulation (PBM) irradiation enhances the therapeutic potential of hMSC spheroids for neural repair.Frontiers in cellular neuroscience · 2026Article
- Transcranial near-infrared therapy restores synaptic resilience by reshaping signaling landscapes in sleep-deprived tauopathy.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026Article
- Efficacy of photobiomodulation therapy in managing iatrogenic trigeminal nerve injury: A retrospective case series.Lasers in medical science · 2025Article
- Photobiomodulation therapy.JADA foundational science · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Photobiomodulation (PBM) is a safe and effective neurotherapy that modulates cellular pathways by altering cell membrane potentials, leading to beneficial biological effects such as anti-inflammatory and neuroregenerative responses. This review compiles studies from PubMed up to March 2024, investigating the impact of light at wavelengths ranging from 620 to 1270 nm on ion channels. Out of 330 articles screened, 19 met the inclusion criteria. Research indicates that PBM can directly affect various ion channels by influencing neurotransmitter synthesis in neighboring cells, impacting receptors like glutamate and acetylcholine, as well as potassium, sodium channels, and transient receptor potential channels. The diversity of studies hampers a comprehensive meta-analysis for evaluating treatment strategies effectively. This systematic review aims to explore the potential role of optoelectronic signal transduction in PBM, studying the neurobiological mechanisms and therapeutic significance of PBM on ion channels. However, the lack of uniformity in current treatment methods underscores the necessity of establishing standardized and reliable therapeutic approaches.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.