ArticleInternational journal of health geographics2024
Light at night exposure and risk of dementia conversion from mild cognitive impairment in a Northern Italy population.
Article in International journal of health geographics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Article
- Associations between wearable-device-measured daytime and nighttime light exposures and dementia risk: A prospective cohort study.General psychiatry · 2026Article
- Spatial Patterns of Opioid Overdose Mortality Risk Across Urban, Transitional, and Rural Communities Using Satellite-Derived and Socioeconomic Indicators.Journal of urban health : bulletin of the New York Academy of Medicine · 2026Article
- Outdoor light at night and neuropsychiatric symptoms in dementia.GeroScience · 2026Article
- The impact of nutritional, environmental, and lifestyle factors on neurological disorders: therapeutic implications and mechanistic insights.Frontiers in pharmacology · 2026Review
- Environmental Factors and Risk of Early-Onset Dementia: A Population-Based Case-Control Study.Neuroepidemiology · 2025Article
- Association between outdoor artificial light at night, circadian health, and LDL-C in intracranial artery atherosclerotic stenosis.Clinical epigenetics · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundA few studies have suggested that light at night (LAN) exposure, i.e. lighting during night hours, may increase dementia risk. We evaluated such association in a cohort of subjects diagnosed with mild cognitive impairment (MCI).
methodsWe recruited study participants between 2008 and 2014 at the Cognitive Neurology Clinic of Modena Hospital, Northern Italy and followed them for conversion to dementia up to 2021. We collected their residential history and we assessed outdoor artificial LAN exposure at subjects' residences using satellite imagery data available from the Visible Infrared Imaging Radiometer Suite (VIIRS) for the period 2014-2022. We assessed the relation between LAN exposure and cerebrospinal fluid biomarkers. We used a Cox-proportional hazards model to compute the hazard ratio (HR) of dementia with 95% confidence interval (CI) according to increasing LAN exposure through linear, categorical, and non-linear restricted-cubic spline models, adjusting by relevant confounders.
resultsOut of 53 recruited subjects, 34 converted to dementia of any type and 26 converted to Alzheimer's dementia. Higher levels of LAN were positively associated with biomarkers of tau pathology, as well as with lower concentrations of amyloid β
conclusionOur findings suggest that outdoor artificial LAN may increase dementia conversion, especially above 30 nW/cm
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.