Trial reportSleep2025
Changes in circadian timing following a 1-week in-home sleep extension manipulation in habitually short-sleeping adolescents.
Trial report in Sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Trial
- Evening Chronotype Is Associated With Daytime Impairment and Differential Sleep and Circadian Response to a Sleep Extension Manipulation in Short Sleeping Adolescents.Journal of sleep research · 2026Trial
- Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings.Journal of visualized experiments : JoVE · 2025Article
- Sex Differences in Circadian Timing and Biological Night in Adolescents.Journal of biological rhythms · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
STUDY
objectivesEvaluate objectively measured circadian rhythms following 1-week of at-home sleep extension in habitually short-sleeping adolescents.
methodsTwenty-six participants (16.1 ± 1.2 years, 69% female, and 65% White non-Hispanic) with insufficient sleep (≤7 h on school nights) were randomized to 1 week of typical sleep (TS; usual school schedule) and sleep extension (EXT; ≥1-h additional time in bed) in counterbalanced order with a 1-month washout between conditions. Home monitoring of actigraphy-estimated sleep and light exposure was assessed during both weeks. Hourly in-laboratory evening/morning dim-light salivary melatonin samples were obtained and onset (DLMOn) and offset (DLMOff) were calculated following each condition.
resultsSleep duration increased by 1.37 h (95% CI = 1.09, 1.66; p < 0.001), bedtimes advanced by 1.40 (95% CI = -1.75, -1.06; p < 0.001), and waketimes did not significantly change (p = 0.055) during EXT compared to TS. There was no change in DLMOn or DLMOff following EXT (both p > 0.05). The DLMOn-sleep onset phase angle narrowed by 0.72 h (95% CI = -1.39, -0.07; p = 0.04) during EXT. Light exposure within 2-h of bedtime was significantly higher during EXT compared to TS (23.37 vs. 7.73 lux; p = 0.048).
conclusionsSleep extension did not change melatonin onset or offset but may have increased circadian alignment. Further research should evaluate the addition of specific strategies to improve circadian timing such as morning bright light in combination with sleep extension.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.