Evidence map›Paper›PMID 39582666›Full record

ArticleFrontiers in nutrition2024

Comparative bioavailability study of supplemental oral Sucrosomial

Nazia M Memon, Gabriele Conti, Elisa Brilli, Germano Tarantino, Muhammad N A Chaudhry, Ameeran Baloch, Areaba Shafiq, Sami U Mumtaz, Wafa Qaisar, Somia Iqtadar and 8 more

2 registry-linked trialsAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06376591 nacompletednot on this map

Assessing the Efficacy of Different Carrier Systems in Oral Vitamin B12 Supplementation in Improving Circulatory B12 Levels in Healthy Adults

TypeinterventionalSponsorLiaquat University of Medical & Health SciencesRan2024 to 2024Enrolled70ConditionsVitamin B 12 DeficiencyArmsVit B12
NCT06983223 nacompletednot on this mapstarted 2025, after this paper: background citation

Oral Sucrosomial® Vitamin B12 in the Management of B12 Deficiency Among Metformin-Treated Type 2 Diabetes Patients: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

TypeinterventionalSponsorLiaquat University of Medical & Health SciencesRan2025 to 2025Enrolled50ConditionsVitamin B 12 Deficiency, Type 2 Diabetes Mellitus (T2DM)ArmsSucrosomial® Vitamin B12, Placebo (Oral)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Nazia M Memon *Department of Pathology, Liaquat University of Medical and Health Sciences (LUMHS), Jamshoro, Pakistan.
Gabriele Conti *Unit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
Elisa BrilliDepartment of R&D, PharmaNutra S.p.A, Pisa, Italy.
Germano TarantinoDepartment of R&D, PharmaNutra S.p.A, Pisa, Italy.
Muhammad N A ChaudhryPunjab Institute of Cardiology, Lahore, Pakistan.
Ameeran BalochNIMRA Cancer Institute, Jamshoro, Pakistan.
Areaba ShafiqDepartment of Psychiatry, Lady Reading Hospital (LRH), Peshawar, Pakistan.
Sami U MumtazDepartment of Medicine, King Edward Medical University (KEMU), Lahore, Pakistan.
Wafa QaisarGulab Devi Hospital, Lahore, Pakistan.
Somia IqtadarDepartment of Medicine, King Edward Medical University (KEMU), Lahore, Pakistan.
Saida AbrarDepartment of Gynecology & Obstetrics, LRH, Peshawar, Pakistan.
Ayesha KanwalDepartment of Psychiatry, Lady Reading Hospital (LRH), Peshawar, Pakistan.
Muhammad H AkhtarPunjab Institute of Cardiology, Lahore, Pakistan.
Hina LatifDepartment of Medicine, King Edward Medical University (KEMU), Lahore, Pakistan.
Fazle RabbaniDepartment of Psychiatry, Lady Reading Hospital (LRH), Peshawar, Pakistan.
Ikram D UjjanDepartment of Pathology, Liaquat University of Medical and Health Sciences (LUMHS), Jamshoro, Pakistan.
Silvia TurroniUnit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
Amjad KhanDepartment of Oncology, University of Oxford, Oxford, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Vitamin B12 is essential for neurological function, red blood cell formation, and DNA synthesis. Deficiency can lead to diverse health conditions, including megaloblastic anemia and neurological issues. Oral supplementation is a standard treatment for B12 deficiency. The Sucrosomial Objectives: This study aimed to compare the effectiveness of oral Sucrosomial Methods: A randomized, double-blind clinical trial was conducted across three centers in Pakistan from April to July 2024. At KEMU, participants received either Sucrosomial Results: Sucrosomial Conclusion: Sucrosomial Clinical trial registration: clinicaltrials.gov, NCT06376591.

Indexed as

oral B12 supplementSucrosomial® technologySucrosomial® vitamin B12vitamin B12 bioavailabilityvitamin B12 deficiency

Identifiers

PMID39582666
PMCPMC11581850

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.