Evidence map›Paper›PMID 39582797›Full record

ArticleBiological psychiatry global open science2025

Effect of an 18-Month Meditation Training on Telomeres in Older Adults: A Secondary Analysis of the Age-Well Randomized Controlled Trial.

Perla Kaliman, María Jesús Álvarez-López, Asrar Lehodey, Daniel Fernández, Anne Chocat, Marco Schlosser, Vincent de La Sayette, Denis Vivien, Natalie L Marchant, Gael Chételat and 3 more

Abstract read
In one paragraph

Article in Biological psychiatry global open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Perla KalimanUniversitat Oberta de Catalonia, Barcelona, Spain.
María Jesús Álvarez-LópezJacinto Benavente. 08100 Mollet del Vallès, Spain.
Asrar LehodeyNormandie Univ., UNICAEN, INSERM, U1237, PhIND Physiopathology and Imaging of Neurological Disorders, NeuroPresage Team, Institut Blood and Brain @ Caen-Normandie, Caen, France.
Daniel FernándezDepartment of Statistics and Operations Research (DEIO), Universitat Politècnica de Catalunya BarcelonaTech (UPC), Barcelona, Spain.
Anne ChocatNormandie Univ., UNICAEN, INSERM, U1237, PhIND Physiopathology and Imaging of Neurological Disorders, NeuroPresage Team, Institut Blood and Brain @ Caen-Normandie, Caen, France.
Marco SchlosserDivision of Psychiatry, University College London, London, United Kingdom.
Vincent de La SayetteDepartment of Neurology, CHU de Caen, Caen, France.
Denis VivienNormandie Univ., UNICAEN, INSERM, U1237, PhIND Physiopathology and Imaging of Neurological Disorders, NeuroPresage Team, Institut Blood and Brain @ Caen-Normandie, Caen, France.
Natalie L MarchantDivision of Psychiatry, University College London, London, England, United Kingdom.
Gael ChételatNormandie Univ., UNICAEN, INSERM, U1237, PhIND Physiopathology and Imaging of Neurological Disorders, NeuroPresage Team, Institut Blood and Brain @ Caen-Normandie, Caen, France.
Antoine LutzEduwell team, Lyon Neuroscience Research Center (CRNL), INSERM U1028, CNRS UMR5292, UCBL1, Lyon, France.
Géraldine PoisnelNormandie Univ., UNICAEN, INSERM, U1237, PhIND Physiopathology and Imaging of Neurological Disorders, NeuroPresage Team, Institut Blood and Brain @ Caen-Normandie, Caen, France.
Medit-Ageing Research Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Shorter telomeres are associated with increased risk of cognitive decline and age-related diseases. Developing interventions to promote healthy aging by preserving telomere integrity is of paramount importance. Here, we investigated the effect of an 18-month meditation intervention on telomere length (TL) measures in older people without cognitive impairment. Methods: A total of 137 adults age ≥65 years were randomized to one of the 3 groups (meditation training, non-native language training, or passive control). We evaluated the 50th and 20th percentile TL and the percentage of critically short telomeres (<3 kbp) in peripheral blood mononuclear cells. Results: Mixed model analysis showed a time effect indicating a general decrease on the 50th percentile TL ( Conclusions: In older adults, we found no evidence for a main effect of an 18-month meditation training program on TL compared with the control groups. Our findings highlight the importance of considering the impact of moderating factors when measuring the effectiveness of meditation-based trainings.

Indexed as

AgingMeditationPBMCPersonalityPreventionRandomized controlled trialTelomere

Identifiers

PMID39582797
PMCPMC11585798

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.