Evidence map›Paper›PMID 39585407›Full record

ArticleDermatologie (Heidelberg, Germany)2024

[Immunohistochemical examinations in malignant melanoma : Fundamentals and special aspects].

Cornelia Sigrid Lissi Müller

Abstract readEnglish Abstract
PubMed Publisher
In one paragraph

Article in Dermatologie (Heidelberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Defensive medicine in dermatological practice - Dermatopathology as a mirror of structural challenges.Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Cornelia Sigrid Lissi MüllerMVZ für Histologie, Zytologie und molekulare Diagnostik Trier GmbH, Max-Planck-Str. 5, 54296, Trier, Deutschland. cornelia.mueller@patho-trier.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunohistochemical examinations have been used for many years in dermatopathology and pathology and have become an integral part of tumor diagnostics. The aim is to identify and classify tumor cells that express distinct antigens. Malignant melanoma can be characterized by a large number of well-described and standardized antibodies, so that immunohistochemical staining is used in the diagnosis of melanoma, the differential diagnosis of other tumors, the determination of tumor thickness, the diagnosis of tumor metastases, and also in the diagnosis of sentinel lymph nodes. Comprehensive knowledge of the expression profiles and specific staining patterns of the antibodies used is of great diagnostic relevance, with the aim of preventing misdiagnosis. The perfect antibody with high sensitivity and maximum specificity does not exist. Hence, immunohistochemistry does not replace the conventional assessment and interpretation of tumor samples. Only in symbiosis with clinical and conventional histological findings do immunohistochemical stains have a diagnostic value.

Indexed as

ImmunohistochemistryMelanomaSkin NeoplasmsBiomarkers, TumorDiagnosis, DifferentialHumansBiomarkers, TumorDedifferentiationImmunohistochemistryImmunophenotypingSpindle cell melanomaTumor diagnostics

Identifiers

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.