Evidence map›Paper›PMID 39587242›Full record

ArticleScientific reports2024

Stratified analysis of the correlation between wedged hepatic venous pressure and portal venous pressure in patients with portal hypertension.

Yifan Lv, Bing Zhu, Dongze Li, Hua Tian, Shaoli You, Sa Lv, Fuchuan Wang, Yongping Yang, Huiguo Ding, Yifan Wu and 3 more

Abstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yifan LvLiver Disease Minimally Invasive Diagnosis and Treatment Center, Beijing Shijitan Hospital, Capital Medical University, No. 10 Tie Yi Road, Yangfangdian, Haidian District, Beijing, 100038, China.
Bing ZhuLiver Vascular Disease Diagnosis and Treatment Center, Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100071, China.
Dongze LiLiver Vascular Disease Diagnosis and Treatment Center, Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100071, China.
Hua TianLiver Vascular Disease Diagnosis and Treatment Center, Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100071, China.
Shaoli YouLiver Vascular Disease Diagnosis and Treatment Center, Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100071, China.
Sa LvLiver Vascular Disease Diagnosis and Treatment Center, Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100071, China.
Fuchuan WangLiver Vascular Disease Diagnosis and Treatment Center, Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100071, China.
Yongping YangLiver Vascular Disease Diagnosis and Treatment Center, Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100071, China.
Huiguo DingDepartment of Gastroenterology and Hepatology, Beijing You'an Hospital Affiliated to Capital Medical University, Beijing, 100069, China.
Yifan WuLiver Disease Minimally Invasive Diagnosis and Treatment Center, Beijing Shijitan Hospital, Capital Medical University, No. 10 Tie Yi Road, Yangfangdian, Haidian District, Beijing, 100038, China.
Chengbin DongLiver Disease Minimally Invasive Diagnosis and Treatment Center, Beijing Shijitan Hospital, Capital Medical University, No. 10 Tie Yi Road, Yangfangdian, Haidian District, Beijing, 100038, China.
Yu ZhangLiver Disease Minimally Invasive Diagnosis and Treatment Center, Beijing Shijitan Hospital, Capital Medical University, No. 10 Tie Yi Road, Yangfangdian, Haidian District, Beijing, 100038, China.
Fuquan LiuLiver Disease Minimally Invasive Diagnosis and Treatment Center, Beijing Shijitan Hospital, Capital Medical University, No. 10 Tie Yi Road, Yangfangdian, Haidian District, Beijing, 100038, China. lfuquan@aliyun.com.

Funding

Beijing Shijitan Hospital 2023LJRCLFQ
6 · The paper itself

Abstract

To evaluate the differences in the agreement between wedged hepatic venous pressure (WHVP) and portal venous pressure (PVP) at different hepatic venous pressure gradient (HVPG) levels to identify specific HVPG thresholds where WHVP can reliably estimate PVP, thus enhancing the accuracy of risk stratification and treatment decision-making for portal hypertension (PHT) patients. A multicenter study of 616 patients with PHT from three centers was stratified into five groups by their HVPG: HVPG < 12 (group A), 12 ≤ HVPG < 16 mmHg (group B), 16 ≤ HVPG < 20 mmHg (group C), 20 ≤ HVPG < 24 mmHg (group D), HVPG ≥ 24 mmHg (group E). Concordance was analyzed using Pearson's correlation coefficient (R), the intraclass correlation coefficient (ICC), and Bland‒Altman analysis in each HVPG stratum. Correlation and agreement between WHVP and PVP varied by HVPG group. Highest agreement was observed in the range of 20 ≤ HVPG < 24 mmHg. (R = 0.55, ICC = 0.68). The proportion of patients with a discrepancy between WHVP and PVP that was greater than 10% of the PVP value was highest in group A (95.7%) and lowest in group D (48.4%). Overestimation of PVP was more common in group E (44.5%), and underestimation of PVP was more common in group A (94.6%). This study does not confirm the usefulness of hepatic vein pressure measurements to predict the PVP and PPG. The means of WHVP and PVP were significantly different in ranges A, B, C, and E.

Indexed as

Hepatic VeinsHypertension, PortalPortal PressureAdultAgedFemaleHumansMaleMiddle AgedPortal VeinVenous PressureHepatic venous pressure gradientPortal hypertensionPortal venous pressureStratified analysisWedged hepatic venous pressure

Identifiers

PMID39587242
PMCPMC11589757

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.