Evidence map›Paper›PMID 39587665›Full record

ReviewJournal of eating disorders2024

Probiotics and eating disorders: a systematic review of humans and animal model studies.

Hossein Bahari, Camellia Akhgarjand, Seyedeh Nooshan Mirmohammadali, Mahsa Malekahmadi

Abstract readReview
In one paragraph

Review in Journal of eating disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Foods (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hossein BahariTransplant Research Center, Clinical Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
Camellia AkhgarjandDepartment of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
Seyedeh Nooshan MirmohammadaliDepartment of Food, Nutrition, Dietetics and Health, Kansas State University, Manhattan, KS, United States.
Mahsa MalekahmadiImam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran. malekahmadimahsa@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEating disorders are complex mental health conditions that significantly impact physical and mental well-being. Current research suggests a potential link between eating disorders and the gut microbiota, highlighting the role of gut-brain communication and its influence on nutrient absorption. Probiotics, which are beneficial bacteria, have shown promise in modulating the gut microbiota and may offer complementary interventions in the treatment of eating disorders.

methodsA comprehensive search was conducted in electronic databases, including PubMed/Medline, Scopus, and Web of Science, from inception to January 2024 to analyze the existing literature on the effects of probiotic supplementation in eating disorders. The search strategy included terms related to probiotics, prebiotics, eating disorders, and food addiction. The human studies were assessed for risk of bias using the Cochrane tool. The quality of animal studies was evaluated using the risk of bias (RoB) tool from the Systematic Review Centre for Laboratory Animal Experimentation.

resultsOf the 417 papers, 12 eligible studies were included comprising five animal and seven clinical studies. Clinical trials ranged from 10 to 20 weeks and were randomized and parallel-arm design. The included studies varied in terms of sample characteristics, intervention types, and outcome measures. Preliminary findings suggest that probiotics may influence gut microbiota composition and may offer support in the treatment of eating disorders.

conclusionsThe reviewed studies showed that probiotic supplementation may have a role in reducing food addiction and binge eating, and enhancing satiety, regulating food intake as well as positively affecting mood. However, further studies with better quality and larger sample size are needed to further validate these findings.

Indexed as

Eating disordersGut microbiotaMental healthPrebioticsProbioticsSystematic review

Identifiers

PMID39587665
PMCPMC11587709

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.