Evidence mapPaperPMID 39588187Full record

SynthesisFrontiers in medicine2024

Scientific landscape of oxidative stress in sarcopenia: from bibliometric analysis to hotspots review.

Linjie Wang, Dongliang Guo, Yi Huang, Pan Long, Xin Zhang, Ling Bai, Jiancheng Liu, Xiaomin Hu, Rizhao Pang, Xiang Gou

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. In Vitro Study on the Effects ofInternational journal of molecular sciences · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Linjie Wang *Department of Rehabilitation Medicine, The General Hospital of Western Theater Command, Sichuan, Chengdu, China.
Dongliang Guo *Department of Rehabilitation Medicine, The General Hospital of Western Theater Command, Sichuan, Chengdu, China.
Yi HuangDepartment of Rehabilitation Medicine, The General Hospital of Western Theater Command, Sichuan, Chengdu, China.
Pan LongSichuan Clinical Medical Research Center for Traditional Chinese Medicine Orthopedics and Sports Medicine Rehabilitation, Sichuan, Chengdu, China.
Xin ZhangDepartment of Rehabilitation Medicine, The General Hospital of Western Theater Command, Sichuan, Chengdu, China.
Ling BaiDepartment of Rehabilitation Medicine, The General Hospital of Western Theater Command, Sichuan, Chengdu, China.
Jiancheng LiuDepartment of Rehabilitation Medicine, The General Hospital of Western Theater Command, Sichuan, Chengdu, China.
Xiaomin HuDepartment of Rehabilitation Medicine, The General Hospital of Western Theater Command, Sichuan, Chengdu, China.
Rizhao PangDepartment of Rehabilitation Medicine, The General Hospital of Western Theater Command, Sichuan, Chengdu, China.
Xiang GouDepartment of Rehabilitation Medicine, The General Hospital of Western Theater Command, Sichuan, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Sarcopenia is a significant healthcare challenge in the aging population. Oxidative stress (OS) is acknowledged to play a pivotal role in the pathological progression of sarcopenia. Numerous studies have demonstrated that mitigating or eliminating OS can ameliorate the pathological manifestations associated with sarcopenia. However, current clinical antioxidant therapies often fall short of anticipated outcomes. This bibliometric analysis aims to delineate prevailing research trends, thematic emphases, focal points, and developmental trajectories within the domain of OS in sarcopenia, while also endeavoring to explore prospective anti-oxidative stress strategies for future clinical interventions. Methods: Relevant publications were retrieved from the Web of Science (WOS) Core Collection database for the period 2000-2024. Citespace was employed for retrieving and analyzing trends and emerging topics. Results: In the field of OS in sarcopenia, the number of publications has significantly increased from 2000 to 2024. The United States and China are the primary contributors to global publication output. The most productive research institution is INRAE. The most prolific author is Holly Van Remmen from the United States, while the most frequently cited author is Cruz-Jentoft AJ from Spain. Experimental Gerontology is the journal with the highest volume of published articles, whereas the Journal of Gerontology Series A: Biological Sciences and Medical Sciences holds the record for the highest number of citations. The research keywords in this field can be categorized into eight domains: "Physiology and anatomy", "Physiological mechanisms", "Pathology associations", "Experimental studies", "Nutrition and metabolism", "Sports and physical activities", "Age" and "Oxidation and antioxidation". Moreover, recent years have seen the emergence of "TNF- Conclusion: This bibliometric and visualization provides a comprehensive analysis of the global research landscape in the field of OS in sarcopenia, identifies priorities, summarizes the current research status and suggests possible future research priorities. In addition, in order to benefit more sarcopenia patients, strengthening cooperation and communication between institutions and research teams is the key to the future development of this field. Given the expectation that research on OS in sarcopenia will remain a prominent area of interest in the future, this article could serve as a valuable resource for scholars seeking to shape future studies through an understanding of influential scholarly contributions and key research findings. Systematic review registration: https://www.crd.york.ac.uk, identifier CRD42024528628.

Indexed as

bibliometricbibliometric analysisCiteSpaceoxidative stresssarcopenia

Identifiers

PMID39588187
PMCPMC11586176

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.