Evidence map›Paper›PMID 39588246›Full record

ArticleCase reports in nephrology2024

Ocular Coherence Tomography Unveils Alport Syndrome: A Critical Tool in Detecting Collagen IV Nephropathies.

Abdelrahman Ibrahim, Zena Altawallbeh, Monica Patricia Revelo, Martin Gregory, Laith Al-Rabadi

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Abdelrahman IbrahimNephrology Department, University of Utah Health, Salt Lake City, Utah, USA.ORCID https://orcid.org/0000-0002-2661-4882
Zena AltawallbehNephrology Department, University of Utah Health, Salt Lake City, Utah, USA.
Monica Patricia ReveloPathology Department, University of Utah Health, Salt Lake City, Utah, USA.
Martin GregoryNephrology Department, University of Utah Health, Salt Lake City, Utah, USA.
Laith Al-RabadiNephrology Department, University of Utah Health, Salt Lake City, Utah, USA.ORCID https://orcid.org/0000-0002-2225-9721

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Collagen IV pathogenic variants are present in Alport syndrome (AS) and some forms of familial focal segmental glomerulosclerosis (FSGS). These conditions pose diagnostic challenges due to overlapping clinical, histological, and genetic features. Ocular coherence tomography (OCT) has emerged as a pivotal diagnostic tool by revealing ocular manifestations characteristic of AS. Here, we present two cases initially diagnosed with primary FSGS but later found to harbor collagen IV pathogenic variants. Both cases progressed to end-stage kidney disease (ESKD) needing transplantation. OCT revealed severe temporal macular thinning consistent with AS in both cases. Our findings highlight the critical role of OCT in distinguishing the subtle differences in the presentation of collagen IV nephropathies. OCT proves valuable for clinicians, particularly when

Identifiers

PMID39588246
PMCPMC11588406

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.