Evidence map›Paper›PMID 39589667›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025

Understanding the impact of early onset colorectal cancer on quality of life: a qualitative analysis of online forum data.

Alice Spencer, Christopher Bedding, Emma Nicklin, Hélène Flint, Alexandra Gilbert

Erratum issuedAbstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Alice SpencerLeeds Institute of Medical Research at St James' Hospital, University of Leeds, Leeds, UK. a.spencer1@leeds.ac.uk.ORCID http://orcid.org/0009-0000-4926-8452
Christopher BeddingLeeds Institute of Medical Research at St James' Hospital, University of Leeds, Leeds, UK.ORCID http://orcid.org/0009-0007-9577-1463
Emma NicklinLeeds Institute of Medical Research at St James' Hospital, University of Leeds, Leeds, UK.ORCID http://orcid.org/0000-0002-6683-8098
Hélène FlintCo-researcher, Hertfordshire, UK.
Alexandra GilbertLeeds Institute of Medical Research at St James' Hospital, University of Leeds, Leeds, UK.ORCID http://orcid.org/0000-0002-9142-1227

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEarly onset colorectal cancer (EOCRC) is rising. The profile of health-related quality of life (HRQOL) impacts may differ in this younger cohort. Online forums are a source of unfiltered information regarding patient experience. This study used a qualitative analysis of online forum messages to elicit the unique HRQOL impacts of EOCRC.

methodsMessages were extracted from an online EOCRC UK forum. Inductive coding (with 10% dual-coding) and thematic analysis were used to describe the impact of diagnosis and treatment on HRQOL.

resultsData extraction and analyses were performed over one month; 463 messages (dated 01/04/2019 to 31/03/2024) were included. There was 100% concordance on dual-coding for main themes. Eight themes emerged: (1) diagnostic pathway and barriers; (2) parenthood and effect on children; (3) employment and finances; (4) fertility and early menopause; (5) stoma implications; (6) support systems, relationships and isolation; (7) sport and exercise and (8) mental health.

conclusionsQualitative thematic analysis of online forum data is a novel and efficient methodology for understanding the impact of cancer on HRQOL. Identified themes overlapped with those published in previous systematic reviews. This study offers new insights into the impact of isolation, early menopause, benefits of parenthood, psychological impact on children and practical and psychological implications of potential infertility in EOCRC. Current understanding of the diagnostic challenges and unique HRQOL impacts of EOCRC raises future research questions regarding how colorectal cancer services should evolve to provide support more in keeping with the needs of this growing younger cohort.

Indexed as

Colorectal NeoplasmsQuality of LifeAdultAge of OnsetFemaleHumansInternetMaleMiddle AgedQualitative ResearchUnited KingdomAdolescentColorectal cancerEarly onsetOnline forumsQuality of lifeYoung adult

Identifiers

PMID39589667
PMCPMC11982157

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.