ReviewJournal of fluorescence2025
Reliability of Multi-Emissive Carbon Quantum Dots for Multiplexing; Assessing the Figures of Merit.
Review in Journal of fluorescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Incredible properties of quantum dots (QDs) have once again been acclaimed with this year's (2023) Nobel prize in chemistry. On the other hand, the invention of multicolour molecular imaging of cell surface receptors for tumour diagnosis by Koyama and group has opened up a new era in diagnostics. Among them carbon quantum dots (CQDs) are interesting class of fluorescent nanomaterials, superior in terms of low toxicity, high solubility and biocompatibility along with simple and cost-effective synthesis processes unlike the traditional metal chalcogenide or perovskite quantum dots. Multi emissive fluorescence property of these carbon quantum dots are very useful in multiplex sensing. Their excellent biocompatibility and low toxicity have attracted researchers to use them extensively for biosensing and imaging of multiple analytes at a time. Core state emission from π-domains and surface state emissions of functional groups surrounding CQDs play a major role in achieving the multicolour emissions and this review discusses the various strategies used to achieve desired multi colour emissions, yet preserving their stability, non-interactive emissive states and quantum yields. Their fine tuning via variation in temperature, pH, time, and heteroatom doping has been comprehensively discussed. A thorough history compared to a list of characteristics for creating effective multicolour CQDs will point us in the proper route. This minireview also assesses the electronic band structure of these multicolour CQDs, their stability with respect to multi emissions, photoluminescence quantum yields, approaches employed for tunability of their optical band gaps, and also enhancement of carrier lifetimes, to arrive at conclusions on the reliability of these materials for multiplexing. The mechanisms namely chemical coupling, FRET, On-Off, Ab-antigen interactions involved in sensing mechanisms involving these materials are analysed in depth. Ultimately, the present obstacles and future directions for the use of these CQDs in sensing applications are discussed.
Indexed as
Identifiers
39589686What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.