Evidence mapPaperPMID 39589992Full record

ArticleBiosensors2024

Electrochemical Determination of B-Type Natriuretic Peptide with an Epitope-Imprinted Polymer-Based Sensor.

Kai-Hsi Liu, James L Thomas, Pei-Chia Chu, Jing-Chen Ciou, Chuen-Yau Chen, Hung-Yin Lin, Mei-Hwa Lee

Abstract read
In one paragraph

Article in Biosensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kai-Hsi LiuDepartment of Electrical Engineering, National University of Kaohsiung, Kaohsiung 81148, Taiwan.
James L ThomasDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, NM 87131, USA.ORCID 0000-0002-2420-7992
Pei-Chia ChuDepartment of Chemical and Materials Engineering, National University of Kaohsiung, Kaohsiung 81148, Taiwan.
Jing-Chen CiouDepartment of Chemical and Materials Engineering, National University of Kaohsiung, Kaohsiung 81148, Taiwan.
Chuen-Yau ChenDepartment of Electrical Engineering, National University of Kaohsiung, Kaohsiung 81148, Taiwan.
Hung-Yin LinDepartment of Chemical and Materials Engineering, National University of Kaohsiung, Kaohsiung 81148, Taiwan.
Mei-Hwa LeeDepartment of Materials Science and Engineering, I-Shou University, Kaohsiung 84001, Taiwan.

Funding

Ministry of Science and Technology of ROC MOST 109-2314-B-390-001-MY3, MOST 110-2221-E-390-003-MY3 and MOST 111-2221-E-214-001-MY3Zuoying Armed Forces General Hospital KAFGH-ZY-A-111003 and KAFGH-ZY-A-112014
6 · The paper itself

Abstract

B-type natriuretic peptides (BNP) are produced and secreted by the myocardium to reduce blood pressure and cardiac load. They cause vasodilation, natriuresis, growth suppression, and inhibition of the sympathetic nervous system and the renin-angiotensin-aldosterone system. The measurement of plasma BNP levels provides clinically useful information concerning the diagnosis and management of left ventricular dysfunction and heart failure, complementing other diagnostic testing procedures. In this work, three epitopes from the N-terminal (BNPnt), C-terminal (BNPct), and the cystine-bridged cyclic peptides (BNPr) of B-type natriuretic peptides were synthesized as templates for molecular imprinting. These peptides were doped into aniline (AN) and m-aminobenzenesulfonic acid (MSAN) for electropolymerization, thus forming epitope-imprinted poly(AN-

Indexed as

Biosensing TechniquesElectrochemical TechniquesNatriuretic Peptide, BrainPolymersAniline CompoundsEpitopesHumansMolecular ImprintingAniline CompoundsEpitopesNatriuretic Peptide, BrainPolymersB-type natriuretic peptideelectrochemical sensingepitope imprintinghuman serum

Identifiers

PMID39589992
PMCPMC11591701

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.