Evidence mapPaperPMID 39591639Full record

ArticleThe American journal of tropical medicine and hygiene2025

Human-Centered Design to Respond to Public Health Crises: Maintaining Canine Rabies Vaccination during the COVID-19 Pandemic in Peru.

Ricardo Castillo-Neyra, Elvis W Díaz, Lizzie Ortiz-Cam, Guillermo Porras, Micaela De La Puente-León, Gian Franco Condori, Olimpia Chuquista-Alcarraz, Sergio E Recuenco, Laura D Tamayo, Alison M Buttenheim and 1 more

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ricardo Castillo-NeyraDepartment of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine at University of Pennsylvania, Philadelphia, Pennsylvania.
Elvis W DíazZoonotic Disease Research Lab, One Health Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru.
Lizzie Ortiz-CamZoonotic Disease Research Lab, One Health Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru.
Guillermo PorrasZoonotic Disease Research Lab, One Health Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru.
Micaela De La Puente-LeónZoonotic Disease Research Lab, One Health Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru.
Gian Franco CondoriZoonotic Disease Research Lab, One Health Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru.
Olimpia Chuquista-AlcarrazNational Epidemiology, Prevention, and Disease Control Center, Ministry of Health, Lima, Peru.
Sergio E RecuencoDepartment of Preventive Medicine and Public Health, Facultad de Medicina San Fernando, Universidad Nacional Mayor de San Marcos, Lima, Peru.
Laura D TamayoZoonotic Disease Research Lab, One Health Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru.
Alison M ButtenheimDepartment of Family and Community Health, School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania.
Valerie A Paz-SoldanZoonotic Disease Research Lab, One Health Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru.

Funding

Spatially responsive mass vaccination strategies for urban rabiesR01AI168291 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Ricardo Castillo Neyra · 2022 to 2026
$3.2M
Research Training in Integration of Epidemiology and Implementation Science for Neglected Zoonotic Disease Control in PeruD43TW012741 · FIC · UNIVERSITY OF PENNSYLVANIA · PI Ricardo Castillo Neyra, Valerie Andrea Paz-Soldan · 2024 to 2026
$723k
Control and Prevention of Zoonotic Epidemics in Cities: A Socio-Spatial ApproachK01AI139284 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI CASTILLO NEYRA, RICARDO · 2019 to 2023
$710k
FIC NIH HHS D43 TW012741NIAID NIH HHS K01 AI139284NIAID NIH HHS R01 AI168291
6 · The paper itself

Abstract

In the early coronavirus disease 2019 pandemic, limited understanding of severe acute respiratory syndrome coronavirus 2 transmission and fears of infection hindered mass dog vaccination efforts in dog rabies-affected areas. Interruption of dog rabies vaccination campaigns could lead to a rapid increase in the risk of human rabies. To address these challenges, we applied human-centered design (HCD) principles to develop a vaccination strategy that prioritizes safety while ensuring dog rabies vaccination continuity in Arequipa, Peru, a rabies-affected area. We describe the process of rapid prototyping and testing undertaken by our research team to adapt the vaccination process in response to a health crisis. A multidisciplinary team met twice a week to prototype a fixed-point vaccination campaign that ensured distancing and reduction of fomite transmission while allowing for the continuation of dog vaccination. Field notes and videos informed successive meetings. The final prototype was used in rabies hotspots. In 4 weeks, six prototypes of safe booths and supporting safety protocols were designed, and two copies of each prototype were field tested. During testing, additional innovations were identified and implemented, including virtual vaccine certificates and online data collection forms. The final prototype was implemented across 251 sites, and 17,876 dogs were vaccinated. Using HCD principles, we swiftly developed a mass vaccination strategy that provided safety and enabled the maintenance of rabies vaccination programs. This work highlights the importance of innovative and adaptive approaches to address public health challenges in times of crisis.

Indexed as

COVID-19Dog DiseasesPublic HealthRabiesRabies VaccinesVaccinationAnimalsDogsHumansMass VaccinationPandemicsPeruSARS-CoV-2Rabies Vaccines

Identifiers

PMID39591639
PMCPMC11803671

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.