ArticleAJNR. American journal of neuroradiology2025
Prolonged Venous Transit on Perfusion Imaging Is Associated with Longer Lengths of Stay in Acute Large Vessel Occlusions.
Article in AJNR. American journal of neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Activity measure post-acute care score for discharge outcomes is associated with prolonged venous transit on perfusion imaging in reperfused large vessel occlusion strokes.PM & R : the journal of injury, function, and rehabilitation · 2026Article
- Imaging Venous Transit Time and Blood-Brain Barrier Permeability of the Deep Brain.Magnetic resonance in medicine · 2026Article
- Baseline prolonged venous transit on CT perfusion predicts the post-treatment Brush Sign after successful reperfusion in acute ischemic stroke patients.Frontiers in neurology · 2026Article
- Unfavorable Perfusion Collateral Impairment Score Is Associated with Higher Odds of Poor Outcomes in Large Vessel Occlusion Stroke.Stroke (Hoboken, N.J.) · 2025Article
- Interobserver and Intraobserver Variability in the Assessment of Prolonged Venous Transit in Anterior Circulation Large-Vessel Occlusion Ischemic Stroke.AJNR. American journal of neuroradiology · 2025Article
- Integrating perfusion imaging derived venous outflow and tissue-level collateral parameters in a comprehensive clinical model enhances prognostication in large vessel occlusion stroke.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Article
- The Cortical Vein Opacification Score Is Independently Associated with Good and Excellent Functional Outcomes at 90 Days in Patients with Minor Stroke with Anterior Circulation Large-Vessel Occlusion: A Multicenter Study.AJNR. American journal of neuroradiology · 2025Article
- Efficacy and safety of mechanical thrombectomy in distal medium middle cerebral artery occlusion ischemic stroke patients on low-dose aspirin.International journal of stroke : official journal of the International Stroke Society · 2025Article
- Prolonged Venous Transit as a Superior Predictor of Functional Outcomes in Successfully Reperfused Large Vessel Occlusions: Comparative Analysis With Cerebral Blood Volume Index and Hypoperfusion Intensity Ratio.Journal of the American Heart Association · 2025Article
- Volume contracted state, mortality and functional outcomes in patients with acute ischaemic stroke due to large vessel occlusion.BMJ neurology open · 2025Article
- Preoperative multimodal CT for selection of acute anterior circulation occlusion stroke patients for mechanical thrombectomy.Frontiers in neurologyArticle
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Authors and funding
25 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeProlonged venous transit (PVT+) is a marker of venous outflow; it is defined as the presence or absence of time-to-maximum ≥10 seconds timing in either the superior sagittal sinus or torcula. This novel perfusion imaging-based metric has been associated with higher odds of mortality and lower odds of functional recovery. This study aims to assess the relationship between PVT on admission perfusion imaging and length of hospital stay in large vessel occlusion strokes successfully reperfused with mechanical thrombectomy. MATERIALS AND
methodsPatients with acute ischemic stroke with large vessel occlusions in the anterior circulation successfully treated with thrombectomy between January 2017 and September 2022 were retrospectively reviewed. The primary outcome was length of stay in the hospital due to the acute stroke event. Univariable and forward stepwise multivariable linear regressions were performed for the primary outcome.
resultsOf 109 patients meeting inclusion, median age was 71 (interquartile range [IQR] 62-80) years. Median hospital length of stay was significantly greater in PVT+ patients (9 [IQR 6-18] days) compared with PVT- patients (6 [IQR 4-12] days,
conclusionsIn successfully reperfused large vessel occlusion strokes, PVT+ was associated with an additional 2 days of hospital stay on average compared with PVT- patients, when adjusting for other clinical covariables. This simple, novel imaging metric is robust in correlating with a range of short- and long-term clinical outcomes.
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