Evidence map›Paper›PMID 39593107›Full record

SynthesisEuropean journal of medical research2024

Diagnostic significance of neutrophil-to-lymphocyte ratio in non-arteritic anterior ischemic optic neuropathy: a meta-analysis.

Erfan Kashani, Shima Nourigheimasi, Jeff Valisno, Isaac Smith, Brandon Lucke-Wold, Hanieh Bazrafshan, Arshin Ghaedi, Amir Mohammad Eghbalnejad Mofrad, Shokoufeh Khanzadeh

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in European journal of medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Erfan KashaniDepartment of Medical Laboratory Sciences, School of Allied Medical Sciences, University of Medical Sciences, Arak, Iran.
Shima NourigheimasiSchool of Medicine, Arak University of Medical Sciences, Arak, Iran.
Jeff ValisnoDepartment of Neurosurgery, University of Florida, Gainesville, USA.
Isaac SmithDepartment of Neurosurgery, University of Florida, Gainesville, USA.
Brandon Lucke-WoldDepartment of Neurosurgery, University of Florida, Gainesville, USA.
Hanieh BazrafshanClinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Arshin GhaediStudent Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Amir Mohammad Eghbalnejad MofradAhvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Shokoufeh KhanzadehTabriz University of Medical Sciences, Tabriz, Iran. khshokufe7@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to determine the association of neutrophil-to-lymphocyte ratio (NLR) with non-arteritic anterior ischemic optic neuropathy (NAION).

methodsWe conducted a systematic review and meta-analysis according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. PubMed, Scopus and Web of Science were searched from the establishment of the database to May 5, 2022 to find the relevant studies. The quality of the included literature was evaluated with the Newcastle-Ottawa scale (NOS). The results are reflected in the form of standard mean difference (SMD) and 95% confidence interval (CI).

resultsFinally, six articles were included in our study. Compared with healthy controls, patients' NLR levels were significantly higher (SMD = 0.47; CI 95% = 0.30-0.65, p<0.001). The included studies were not statistically heterogeneous (I

conclusionsOur findings suggest NLR to be a potential marker of NAION, while also implicating a role for inflammation in underlying pathophysiology.

Indexed as

LymphocytesNeutrophilsOptic Neuropathy, IschemicBiomarkersHumansLymphocyte CountBiomarkers

Identifiers

PMID39593107
PMCPMC11600861

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.