Evidence map›Paper›PMID 39593188›Full record

ArticleBMC research notes2024

Identification of fungal pathogens among COVID-19 and non COVID-19 cases in Bhaktapur hospital, Nepal.

Asmita Lamichhane, Sushma Regmi, Krishma Pandit, Sweety Upadhaya, Jyoti Acharya, Srijana Koirala, Shreedhar Aryal, Krishna Gurung, Jiwan Thapa, Sanjib Adhikari and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Aflatoxin-producingIranian journal of microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Asmita LamichhaneCentral Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal.
Sushma RegmiCentral Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal.
Krishma PanditCentral Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal.
Sweety UpadhayaNational Public Health Laboratory, Teku, Kathmandu, Nepal.
Jyoti AcharyaNational Public Health Laboratory, Teku, Kathmandu, Nepal.
Srijana KoiralaBhaktapur Hospital, Bhaktapur, Nepal.
Shreedhar AryalBhaktapur Hospital, Bhaktapur, Nepal.
Krishna GurungPrithvi Narayan Campus, Pokhara, Nepal.
Jiwan ThapaWestern Regional Hospital, Pokhara, Nepal.
Sanjib AdhikariCentral Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal.
Suprina SharmaCentral Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal.
Pramod PoudelCentral Department of Biotechnology, Tribhuvan University, Kathmandu, Nepal.
Supriya SharmaCentral Department of Microbiology, Tribhuvan University, Kirtipur, Kathmandu, Nepal. supriya.sharma@cdmi.tu.edu.np.

Funding

University Grants Commission- Nepal UGC Collaborative Research Grant Program (PI-Dr. Supriya Sharma) Grant no.CRG-78/79-S&T-02
6 · The paper itself

Abstract

objectivesPatients with coronavirus disease 2019 (COVID-19) are at increased risk of opportunistic fungal infections. This study aims to identify fungal pathogens among COVID positive and negative patients, assess their antifungal susceptibility and evaluate biofilm forming ability of Candida spp. A cross-sectional study was conducted among sputum samples from 135 COVID positive and 101 COVID negative cases. Fungal pathogens were identified by conventional culture methods. Antifungal susceptibility test of Candida isolates was done by disc diffusion method and biofilm production by microtiter plate method.

resultsThe prevalence of fungal pathogens among COVID-positive and negative cases was 6.70% and 22.77% respectively. In COVID positive cases, Candida albicans (33.33%) was predominantly followed by Aspergillus flavus 2(22.22%) and Candida tropicalis, Mucor spp. and Aspergillus fumigatus. In COVID negative cases, Candida albicans (69.60%) prevailed followed by Trichosporon spp., Candida parapsilosis, Mucor and Alternaria. Age and gender were not associated with fungal infection. Most Candida spp. were susceptible to miconazole but resistant to ketoconazole. To the best of our knowledge, this study represents the first report from Nepal on critical and high priority fungal pathogens categorized by WHO. With fungal infections on the rise, enhanced clinical vigilanceand antifungal susceptibility testing are warranted.

Indexed as

Antifungal AgentsCOVID-19AdultAgedAspergillus flavusAspergillus fumigatusCandidaCandida albicansCandida tropicalisCross-Sectional StudiesFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedMucorAntifungal AgentsAntifungal susceptibility testingCOVID-19Critical and high priority pathogensFungal infection

Identifiers

PMID39593188
PMCPMC11600556

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.