Evidence map›Paper›PMID 39594538›Full record

ReviewAntioxidants (Basel, Switzerland)2024

Oxidative Stress in Canine Diseases: A Comprehensive Review.

Perez-Montero Blanca, Fermín-Rodriguez María Luisa, Miró Guadalupe, Cruz-Lopez Fátima

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
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  11. Exploring specific biomarkers in blood forFrontiers in microbiology · 2026
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Perez-Montero BlancaClinical Pathology Service, Veterinary Teaching Hospital, Complutense University, 28040 Madrid, Spain.ORCID 0000-0002-9041-0470
Fermín-Rodriguez María LuisaClinical Pathology Service, Veterinary Teaching Hospital, Complutense University, 28040 Madrid, Spain.
Miró GuadalupeAnimal Health Department, Faculty of Veterinary Medicine, Complutense University, 28040 Madrid, Spain.ORCID 0000-0003-0981-2470
Cruz-Lopez FátimaVISAVET Health Surveillance Centre, Complutense University, 28040 Madrid, Spain.ORCID 0000-0002-1142-3944

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress (OS), defined as a disruption in redox balance favoring oxidants, has emerged as a major contributor to numerous diseases in human and veterinary medicine. While several reviews have explored the implication of OS in human pathology, an exhaustive review of the canine species is lacking. This comprehensive review aims to summarize the existing literature on the role of OS in canine diseases, highlighting its potentially detrimental effect on various organs and systems. Some inconsistencies among studies exist, likely due to varying biomarkers and sample types. However, there is substantial evidence supporting the involvement of OS in the development or progression of numerous canine disorders, such as cardiovascular, oncologic, endocrine, gastrointestinal, hematologic, renal, neurologic, infectious, and parasitic diseases, among others. Additionally, this review discusses the efficacy of antioxidant and pro-oxidant therapeutic agents for these conditions. Dietary interventions to counteract OS in dogs have gained significant attention in recent years, although further research on the topic is needed. This review aims to serve as a foundational resource for future investigations in this promising field.

Indexed as

antioxidantsdogfree radicalsoxidationredoxveterinary medicine

Identifiers

PMID39594538
PMCPMC11591346

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.