Evidence map›Paper›PMID 39595024›Full record

ArticleBiomedicines2024

Specific and Polyfunctional T Cell Response Against

Léonie Lesec, Julien Serrier, Célia Seillier, Benoit Bernay, Caroline Regnauld, Jonathane Furon, Jérôme Leprince, Benjamin Lefranc, Denis Vivien, Fabian Docagne and 2 more

Abstract read
In one paragraph

Article in Biomedicines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Léonie LesecNormandie Univ, UNICAEN, INSERM, GIP Cyceron, Institut Blood and Brain @Caen-Normandie (BB@C), UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), 14032 Caen, France.
Julien SerrierNormandie Univ, UNICAEN, INSERM, GIP Cyceron, Institut Blood and Brain @Caen-Normandie (BB@C), UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), 14032 Caen, France.ORCID 0000-0003-0507-0254
Célia SeillierNormandie Univ, UNICAEN, INSERM, GIP Cyceron, Institut Blood and Brain @Caen-Normandie (BB@C), UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), 14032 Caen, France.ORCID 0000-0002-5965-3626
Benoit BernayNormandie Univ, UNICAEN, US EMerode, Plateform Proteogen, 14000 Caen, France.
Caroline RegnauldNormandie Univ, UNICAEN, INSERM, GIP Cyceron, Institut Blood and Brain @Caen-Normandie (BB@C), UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), 14032 Caen, France.ORCID 0000-0002-0359-3302
Jonathane FuronNormandie Univ, UNICAEN, INSERM, GIP Cyceron, Institut Blood and Brain @Caen-Normandie (BB@C), UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), 14032 Caen, France.
Jérôme LeprinceNormandie Univ, UNIROUEN, INSERM, U1239 NorDiC, Neuronal and Neuroendocrine Differentiation and Communication, 76000 Rouen, France.ORCID 0000-0002-7814-9927
Benjamin LefrancNormandie Univ, UNIROUEN, INSERM, US51 HeRacLeS, PRIMACEN, 76000 Rouen, France.ORCID 0000-0002-0367-2414
Denis VivienNormandie Univ, UNICAEN, INSERM, GIP Cyceron, Institut Blood and Brain @Caen-Normandie (BB@C), UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), 14032 Caen, France.ORCID 0000-0002-7636-2185
Fabian DocagneNormandie Univ, UNICAEN, INSERM, GIP Cyceron, Institut Blood and Brain @Caen-Normandie (BB@C), UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), 14032 Caen, France.
Brigitte Le MauffNormandie Univ, UNICAEN, INSERM, GIP Cyceron, Institut Blood and Brain @Caen-Normandie (BB@C), UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), 14032 Caen, France.
Olivier ToutiraisNormandie Univ, UNICAEN, INSERM, GIP Cyceron, Institut Blood and Brain @Caen-Normandie (BB@C), UMR-S U1237, Physiopathology and Imaging of Neurological Disorders (PhIND), 14032 Caen, France.ORCID 0000-0002-9591-8548

Funding

Etablissement Français du Sang, France no grant number
6 · The paper itself

Abstract

backgroundAnti-

resultsIn this mouse model, we identified anti-GluN1-specific CD4

conclusionsThis study identified, for the first time, a potential contribution of T helper cells in the pathology of NMDAR AE and paved the way for the development of future tolerogenic approaches to treat relapses.

Indexed as

autoimmune encephalitisB cellsN-methyl-d-aspartate receptorT cells

Identifiers

PMID39595024
PMCPMC11591936

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.