Evidence map›Paper›PMID 39596194›Full record

ArticleInternational journal of molecular sciences2024

Use of 3' Rapid Amplification of cDNA Ends (3' RACE)-Based Targeted RNA Sequencing for Profiling of Druggable Genetic Alterations in Urothelial Carcinomas.

Natalia V Mitiushkina, Vladislav I Tiurin, Aleksandra A Anuskina, Natalia A Bordovskaya, Ekaterina A Nalivalkina, Darya M Terina, Mariya V Berkut, Anna D Shestakova, Maria V Syomina, Ekaterina Sh Kuligina and 2 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Natalia V MitiushkinaDepartment of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.ORCID 0000-0002-0179-3191
Vladislav I TiurinDepartment of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.ORCID 0000-0002-0157-5952
Aleksandra A AnuskinaDepartment of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.
Natalia A BordovskayaDepartment of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.ORCID 0009-0003-5583-4221
Ekaterina A NalivalkinaDepartment of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.ORCID 0009-0000-1955-1433
Darya M TerinaDepartment of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.
Mariya V BerkutDepartment of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.ORCID 0000-0002-6276-1716
Anna D ShestakovaDepartment of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.
Maria V SyominaDepartment of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.ORCID 0009-0003-3206-2871
Ekaterina Sh KuliginaDepartment of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.ORCID 0000-0002-2396-6540
Alexandr V TogoDepartment of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.
Evgeny N ImyanitovDepartment of Tumor Growth Biology, N.N. Petrov Institute of Oncology, 197758 St. Petersburg, Russia.ORCID 0000-0003-4529-7891

Funding

Russian Science Foundation 22-15-00487
6 · The paper itself

Abstract

Targeted treatment of advanced or metastatic urothelial carcinomas (UCs) requires the identification of druggable mutations. This study describes the development of a 3' Rapid Amplification of cDNA Ends (3' RACE)-based targeted RNA sequencing panel which accounts for the status of all genes relevant to UC treatment, namely,

Indexed as

Sequence Analysis, RNAAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedMutationReceptor, Fibroblast Growth Factor, Type 2Receptor, Fibroblast Growth Factor, Type 3Urinary Bladder NeoplasmsFGFR3 protein, humanReceptor, Fibroblast Growth Factor, Type 2Receptor, Fibroblast Growth Factor, Type 3amplificationbladder cancerFGFR2FGFR3fusionHER2mutationNGStargeted RNA sequencingurothelial carcinoma

Identifiers

PMID39596194
PMCPMC11594887

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.