Evidence map›Paper›PMID 39596263›Full record

ReviewInternational journal of molecular sciences2024

Abnormalities of Oocyte Maturation: Mechanisms and Implications.

Giorgio Maria Baldini, Dario Lot, Antonio Malvasi, Antonio Simone Laganà, Antonella Vimercati, Miriam Dellino, Ettore Cicinelli, Domenico Baldini, Giuseppe Trojano

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Giorgio Maria BaldiniObstetrics and Gynecology Unit, Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro", 70121 Bari, Italy.ORCID 0000-0002-5061-8007
Dario LotIVF Center, Momo Fertilife, 76011 Bisceglie, Italy.
Antonio MalvasiObstetrics and Gynecology Unit, Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro", 70121 Bari, Italy.
Antonio Simone LaganàUnit of Obstetrics and Gynecology "Paolo Giacone" Hospital, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialities (PROMISE), University of Palermo, 90135 Palermo, Italy.ORCID 0000-0003-1543-2802
Antonella VimercatiObstetrics and Gynecology Unit, Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro", 70121 Bari, Italy.ORCID 0000-0002-9862-1619
Miriam DellinoObstetrics and Gynecology Unit, Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro", 70121 Bari, Italy.
Ettore CicinelliObstetrics and Gynecology Unit, Department of Biomedical Sciences and Human Oncology, University of Bari "Aldo Moro", 70121 Bari, Italy.ORCID 0000-0003-2390-4582
Domenico BaldiniIVF Center, Momo Fertilife, 76011 Bisceglie, Italy.ORCID 0000-0003-1433-504X
Giuseppe TrojanoDepartment of Maternal and Child Health, Madonna delle Grazie Hospital, 75010 Matera, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The elucidation of oocyte maturation mechanisms is paramount for advancing embryo development within the scope of assisted reproductive technologies (ART). Both cytoplasmic and nuclear maturation represent intricate processes governed by tightly regulated cellular pathways, which are essential for ensuring the oocyte's competence for fertilization and subsequent embryogenesis. A comprehensive grasp of these mechanisms is vital, as the maturation stage of the oocyte significantly influences chromosomal integrity, spindle formation, and its ability to support the initial stages of embryonic development. By leveraging this knowledge, we can enhance in vitro fertilization (IVF) protocols, refining ovarian stimulation regimens and culture conditions to improve oocyte quality. This, in turn, has the potential to boost pregnancy rates and outcomes. Further research in this area will contribute to the development of novel interventions that aim to increase the efficacy of preimplantation embryonic development, offering new opportunities for individuals undergoing fertility treatments.

Indexed as

Embryonic DevelopmentOocytesAnimalsFemaleFertilization in VitroHumansIn Vitro Oocyte Maturation TechniquesOogenesisPregnancyabnormalities oocyte maturationassisted reproductive technologies (ART)in vitro fertilization (IVF)oocyte maturation

Identifiers

PMID39596263
PMCPMC11595025

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.