Evidence map›Paper›PMID 39596271›Full record

ArticleInternational journal of molecular sciences2024

Relationship Between the Occurrence of Depression and

Mateusz Kowalczyk, Edward Kowalczyk, Monika Talarowska, Ireneusz Majsterek, Maciej Skrzypek, Tomasz Popławski, Monika Sienkiewicz, Anna Wiktorowska-Owczarek, Paulina Sokołowska, Marta Jóźwiak-Bębenista

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mateusz KowalczykBabinski Memorial Hospital, ul. Aleksandrowska 159, 91-229 Lodz, Poland.
Edward KowalczykDepartment of Pharmacology and Toxicology, Medical University of Lodz, ul. Zeligowskiego 7/9, 90-752 Lodz, Poland.ORCID 0000-0002-2250-6040
Monika TalarowskaDepartment of Clinical Psychology and Psychopathology, Institute of Psychology, University of Lodz, ul. Scheiblerow 2, 90-128 Lodz, Poland.ORCID 0000-0002-3451-1250
Ireneusz MajsterekDepartment of Clinical Chemistry and Biochemistry, Medical University of Lodz, ul. Mazowiecka 5, 92-215 Lodz, Poland.
Maciej SkrzypekDepartment of Clinical Chemistry and Biochemistry, Medical University of Lodz, ul. Mazowiecka 5, 92-215 Lodz, Poland.
Tomasz PopławskiDepartment of Microbiology and Pharmaceutical Biochemistry, Medical University of Lodz, ul. Mazowiecka 5, 92-215 Lodz, Poland.ORCID 0000-0003-2300-7339
Monika SienkiewiczDepartment of Pharmaceutical Microbiology and Microbiological Diagnostics, Medical University of Lodz, ul. Muszynskiego 1, 90-151 Lodz, Poland.ORCID 0000-0002-9823-4176
Anna Wiktorowska-OwczarekDepartment of Pharmacology and Toxicology, Medical University of Lodz, ul. Zeligowskiego 7/9, 90-752 Lodz, Poland.ORCID 0000-0003-3452-5748
Paulina SokołowskaDepartment of Pharmacology and Toxicology, Medical University of Lodz, ul. Zeligowskiego 7/9, 90-752 Lodz, Poland.
Marta Jóźwiak-BębenistaDepartment of Pharmacology and Toxicology, Medical University of Lodz, ul. Zeligowskiego 7/9, 90-752 Lodz, Poland.ORCID 0000-0001-9032-1438

Funding

Statutory activity of Medical University of Lodz, Poland 503/1-108-01/503-11-001
6 · The paper itself

Abstract

Although the epidemiology and symptoms of major depressive disorder (MDD) have been well-documented, the etiology and pathophysiology of the disease have not yet been fully explained. Depression arises from intricate interplay among social, psychological, and biological factors. Recently, there has been growing focus on the involvement of miRNAs in depression, with suggestions that abnormal miRNA processing locally at the synapse contributes to MDD. Changes in miRNAs may result from altered expression and/or function of the miRNA biogenesis machinery at the synapse. The aim of our research was to assess the relationship between the occurrence of depression and single-nucleotide polymorphisms (SNP) in the following genes in the Polish population:

Indexed as

Genetic Predisposition to DiseaseKaryopherinsPolymorphism, Single NucleotideRibonuclease IIIAdultCase-Control StudiesDepressionFemaleGene FrequencyGenotypeHumansMajor Depressive DisorderMaleMiddle AgedPolandDROSHA protein, humanKaryopherinsRibonuclease IIIXPO5 protein, humanDROSHAmajor depressive disorder (MDD)miRNA machinery genessingle-nucleotide polymorphismXPO5

Identifiers

PMID39596271
PMCPMC11594337

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.