Evidence mapPaperPMID 39596344Full record

ArticleInternational journal of molecular sciences2024

Population Pharmacokinetic Model of Vitamin D

Stacey M Tuey, Avisek Ghimire, Serge Guzy, Linda Prebehalla, Amandla-Atilano Roque, Gavriel Roda, Raymond E West, Michel B Chonchol, Nirav Shah, Thomas D Nolin and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Stacey M TueyDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO 80045, USA.
Avisek GhimireDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO 80045, USA.
Serge GuzyPop-Pharm Pharmacometrics Service, Albany, CA 94706, USA.
Linda PrebehallaCenter for Clinical Pharmaceutical Sciences, Department of Pharmacy and Therapeutics, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA.ORCID 0009-0003-2887-4615
Amandla-Atilano RoqueDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO 80045, USA.
Gavriel RodaDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO 80045, USA.
Raymond E WestCenter for Clinical Pharmaceutical Sciences, Department of Pharmacy and Therapeutics, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Michel B ChoncholDivision of Renal Diseases and Hypertension, University of Colorado, Aurora, CO 80045, USA.
Nirav ShahDepartment of Medicine Renal Electrolyte Division, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Thomas D NolinCenter for Clinical Pharmaceutical Sciences, Department of Pharmacy and Therapeutics, School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15261, USA.ORCID 0000-0003-4339-1382
Melanie S JoyDepartment of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO 80045, USA.

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · 2025 to 2025
$10.1M
NCATS NIH HHS UL1 TR001857NCATS NIH HHS UL1 TR002535NIGMS NIH HHS R01 GM107122NIH R01 GM107122
6 · The paper itself

Abstract

Vitamin D insufficiency and deficiency are highly prevalent in patients with chronic kidney disease (CKD), and their pharmacokinetics are not well described. The primary study objective was to develop a population pharmacokinetic model of oral cholecalciferol (VitD

Indexed as

CholecalciferolRenal Insufficiency, ChronicVitamin D DeficiencyAdministration, OralAdultAgedCalcifediolFemaleHumansMaleMiddle AgedModels, BiologicalCalcifediolCholecalciferolcholecalciferolchronic kidney diseasepopulation pharmacokinetic modelvitamin D deficiency

Identifiers

PMID39596344
PMCPMC11595143

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.