Evidence map›Paper›PMID 39596404›Full record

ReviewInternational journal of molecular sciences2024

The Oral Microbiota, Microbial Metabolites, and Immuno-Inflammatory Mechanisms in Cardiovascular Disease.

Zheng Wang, Robert C Kaplan, Robert D Burk, Qibin Qi

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. The Role ofBiomedicines · 2026
    Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. COPD-Lung Cancer Comorbidity: Mechanistic Insights and Precision Oncology Implications.International journal of chronic obstructive pulmonary disease · 2026
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Cancers · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zheng WangDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0000-0003-2052-5552
Robert C KaplanDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Robert D BurkDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Qibin QiDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

Funding

Integrated analysis of CVD risk in HIV: gut microbiota, immune function and metabolitesR01HL140976 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KAPLAN, ROBERT C, KNIGHT, ROB · 2018 to 2021
$3.3M
Multi-omic signatures of gut dysbiosis and cardiovascular comorbidities associated with HIV infectionR01HL170904 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Robert D Burk, JORGE R KIZER · 2023 to 2026
$2.9M
Multiomics analysis of the microbiome and subclinical cardiovascular disease in HIV infectionK01HL169019 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Zheng Wang · 2024 to 2026
$497k
NHLBI NIH HHS K01 HL169019NHLBI NIH HHS R01 HL140976NHLBI NIH HHS R01 HL170904
6 · The paper itself

Abstract

Cardiovascular diseases (CVDs) remain a leading cause of global morbidity and mortality. Recent advancements in high-throughput omics techniques have enhanced our understanding of the human microbiome's role in the development of CVDs. Although the relationship between the gut microbiome and CVDs has attracted considerable research attention and has been rapidly evolving in recent years, the role of the oral microbiome remains less understood, with most prior studies focusing on periodontitis-related pathogens. In this review, we summarized previously reported associations between the oral microbiome and CVD, highlighting known CVD-associated taxa such as

Indexed as

Cardiovascular DiseasesMouthAnimalsGastrointestinal MicrobiomeHumansInflammationMicrobiotacardiovascular diseasesgut microbiomeinflammatory markersmicrobial metabolitesoral microbiome

Identifiers

PMID39596404
PMCPMC11594421

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.