Evidence map›Paper›PMID 39596474›Full record

ReviewInternational journal of molecular sciences2024

The Interplay of Stress, Inflammation, and Metabolic Factors in the Course of Parkinson's Disease.

Tal Ben Shaul, Dan Frenkel, Tanya Gurevich

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tal Ben ShaulMovement Disorders Center, Neurological Institute, Tel Aviv Medical Center, Tel Aviv 6423906, Israel.
Dan FrenkelDepartment of Neurobiology, School of Neurobiology, Biochemistry and Biophysics, Tel Aviv University, Ramat-Aviv, Tel Aviv 6997801, Israel.
Tanya GurevichMovement Disorders Center, Neurological Institute, Tel Aviv Medical Center, Tel Aviv 6423906, Israel.ORCID 0000-0003-2092-9848

Funding

Prof Dan frenkel is a guest editor Prof Dan frenkel is a guest editor
6 · The paper itself

Abstract

Parkinson's disease (PD) is a prevalent neurodegenerative condition for which there are symptomatic treatments but no disease-modifying therapies (DMTs). Extensive research over the years has highlighted the need for a multi-target DMT approach in PD that recognizes the various risk factors and their intricate interplay in contributing to PD-related neurodegeneration. Widespread risk factors, such as emotional stress and metabolic factors, have increasingly become focal points of exploration. Our review aims to summarize interactions between emotional stress and selected key players in metabolism, such as insulin, as potential mechanisms underlying neurodegeneration in PD.

Indexed as

InflammationParkinson DiseaseStress, PsychologicalAnimalsHumansRisk Factorsdiabetesdopaminergic degenerationinsulin signaling and resistancemetabolic factorsneurodegenerationneuroinflammationParkinson’s diseasephysiological stresspsychological stress

Identifiers

PMID39596474
PMCPMC11594997

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.