Evidence map›Paper›PMID 39596729›Full record

ReviewAntibiotics (Basel, Switzerland)2024

Antibiotic-Induced Immunosuppression-A Focus on Cellular Immunity.

Timothy Arthur Chandos Snow, Mervyn Singer, Nishkantha Arulkumaran

Abstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Diagnostic accuracy of radiolabelled-WBC scintigraphy in patients with antibiotic therapy.European journal of nuclear medicine and molecular imaging · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Peri-Operative Antimicrobial Prophylaxis Modulates CD4Antibiotics (Basel, Switzerland) · 2025
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Timothy Arthur Chandos SnowBloomsbury Institute of Intensive Care Medicine, University College London, London WC1E 6DH, UK.ORCID 0000-0002-8395-7857
Mervyn SingerBloomsbury Institute of Intensive Care Medicine, University College London, London WC1E 6DH, UK.ORCID 0000-0002-1042-6350
Nishkantha ArulkumaranBloomsbury Institute of Intensive Care Medicine, University College London, London WC1E 6DH, UK.ORCID 0000-0001-7942-8007

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotics are the fundamental treatment for bacterial infections. However, they are associated with numerous side effects. Their adverse effects on the immune system are increasingly recognised, with several mechanisms identified. In this review, we focus on their direct effects on cellular immunity. We review the effects of antibiotics on mitochondrial function and how they impair specific immune cell functions including chemotaxis, phagocytosis, cytokine production, antigen presentation, and lymphocyte proliferation. Findings are described in a multitude of

Indexed as

antimicrobialcritical illnessimmune responseinfectionlymphocytemonocytesepsis

Identifiers

PMID39596729
PMCPMC11591424

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.