Evidence map›Paper›PMID 39596986›Full record

ArticleMedicina (Kaunas, Lithuania)2024

Perindopril Ameliorates Sodium Valproate-Induced Rat Model of Autism: Involvement of Sirtuin-1, JAK2/STAT3 Axis, PI3K/Akt/GSK-3β Pathway, and PPAR-Gamma Signaling.

Anwar M Alnakhli, Asmaa Saleh, Ahmed M Kabel, Remon S Estfanous, Hany M Borg, Khulud M Alsufyani, Nesreen M Sabry, Fatma Alzahraa M Gomaa, Maaly A Abd Elmaaboud

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anwar M AlnakhliDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.
Asmaa SalehDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.ORCID 0000-0002-6286-319X
Ahmed M KabelDepartment of Pharmacology, Faculty of Medicine, Tanta University, Tanta 31527, Egypt.ORCID 0000-0002-5101-8011
Remon S EstfanousAnatomy and Embryology Department, Faculty of Medicine, Tanta University, Tanta 31527, Egypt.
Hany M BorgPhysiology Department, Faculty of Medicine, Kafrelsheikh University, Kafr El-Shaikh 33516, Egypt.
Khulud M AlsufyaniTaif Medical Center, Taif 26526, Saudi Arabia.
Nesreen M SabryClinical Oncology Department, Faculty of Medicine, Tanta University, Tanta 31527, Egypt.
Fatma Alzahraa M GomaaPharamcognosy and Medicinal Herbs Department, Faculty of Pharmacy, Al-Baha University, AlBaha 65779, Saudi Arabia.
Maaly A Abd ElmaaboudDepartment of Pharmacology, Faculty of Medicine, Tanta University, Tanta 31527, Egypt.ORCID 0000-0002-8057-3014

Funding

Princess Nourah bint Abdulrahman University PNURSP2024R489
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Autistic DisorderDisease Models, AnimalGlycogen Synthase Kinase 3 betaJanus Kinase 2PerindoprilPPAR gammaSignal TransductionSirtuin 1STAT3 Transcription FactorValproic AcidAnimalsFemaleHippocampusMaleOxidative StressPhosphatidylinositol 3-KinasesGlycogen Synthase Kinase 3 betaJak2 protein, ratJanus Kinase 2PerindoprilPhosphatidylinositol 3-KinasesPPAR gammaProto-Oncogene Proteins c-aktSirtuin 1STAT3 Transcription FactorValproic Acidapoptosisautismneuroinflammationperindoprilratsvalproic acid

Identifiers

PMID39596986
PMCPMC11596946

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.