Evidence map›Paper›PMID 39597692›Full record

ReviewMicroorganisms2024

Regulation of Milk Fat Synthesis: Key Genes and Microbial Functions.

Ye Yu, Runqi Fu, Chunjia Jin, Huan Gao, Lin Han, Binlong Fu, Min Qi, Qian Li, Zhuo Suo, Jing Leng

Abstract readReview
In one paragraph

Review in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ye YuFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.ORCID 0000-0002-2517-1282
Runqi FuFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Chunjia JinFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Huan GaoFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Lin HanFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Binlong FuFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Min QiFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Qian LiFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Zhuo SuoFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.
Jing LengFaculty of Animal Science and Technology, Yunnan Agricultural University, Kunming 650201, China.

Funding

Joint Funds of the National Natural Science Foundation of China U2202203Key Project of Basic Research Program of Science and Technology Department of Yunnan Province 202201AS070063the National Natural Science Foundation of China 32260841Yunnan Revitalization Talent Support Program 202305AS350024
6 · The paper itself

Abstract

Milk is rich in a variety of essential nutrients, including fats, proteins, and trace elements that are important for human health. In particular, milk fat has an alleviating effect on diseases such as heart disease and diabetes. Fatty acids, the basic units of milk fat, play an important role in many biological reactions in the body, including the involvement of glycerophospholipids and sphingolipids in the formation of cell membranes. However, milk fat synthesis is a complex biological process involving multiple organs and tissues, and how to improve milk fat of dairy cows has been a hot research issue in the industry. There exists a close relationship between milk fat synthesis, genes, and microbial functions, as a result of the organic integration between the different tissues of the cow's organism and the external environment. This review paper aims (1) to highlight the synthesis and regulation of milk fat by the first and second genomes (gastrointestinal microbial genome) and (2) to discuss the effects of ruminal microorganisms and host metabolites on milk fat synthesis. Through exploring the interactions between the first and second genomes, and discovering the relationship between microbial and host metabolite in the milk fat synthesis pathway, it may become a new direction for future research on the mechanism of milk fat synthesis in dairy cows.

Indexed as

cowsgenesmetabolitesmicroorganismsmilk fat

Identifiers

PMID39597692
PMCPMC11596427

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.