Evidence map›Paper›PMID 39597982›Full record

ReviewJournal of clinical medicine2024

The Unique Challenge of Coronary Artery Disease in Adult Patients with Congenital Heart Disease.

Nunzia Borrelli, Assunta Merola, Rosaria Barracano, Michela Palma, Ippolita Altobelli, Massimiliana Abbate, Giovanni Papaccioli, Giovanni Domenico Ciriello, Carmen Liguori, Davide Sorice and 3 more

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Empowering congenital heart disease treatment: Physical activity prescription. The Italian proposal.International journal of cardiology. Congenital heart disease · 2026
    Article
  3. New perspectives in the management of adults with congenital heart disease: insights from the 2025 ACHD Congress.European heart journal supplements : journal of the European Society of Cardiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Nunzia BorrelliAdult Congenital Heart Disease and Familiar Arrhythmias Unit, Monaldi Hospital, 80131 Naples, Italy.
Assunta MerolaAdult Congenital Heart Disease and Familiar Arrhythmias Unit, Monaldi Hospital, 80131 Naples, Italy.
Rosaria BarracanoAdult Congenital Heart Disease and Familiar Arrhythmias Unit, Monaldi Hospital, 80131 Naples, Italy.
Michela PalmaAdult Congenital Heart Disease and Familiar Arrhythmias Unit, Monaldi Hospital, 80131 Naples, Italy.
Ippolita AltobelliAdult Congenital Heart Disease and Familiar Arrhythmias Unit, Monaldi Hospital, 80131 Naples, Italy.
Massimiliana AbbateAdult Congenital Heart Disease and Familiar Arrhythmias Unit, Monaldi Hospital, 80131 Naples, Italy.
Giovanni PapaccioliAdult Congenital Heart Disease and Familiar Arrhythmias Unit, Monaldi Hospital, 80131 Naples, Italy.ORCID 0000-0002-7416-9728
Giovanni Domenico CirielloAdult Congenital Heart Disease and Familiar Arrhythmias Unit, Monaldi Hospital, 80131 Naples, Italy.ORCID 0000-0001-6115-9435
Carmen LiguoriAdult Congenital Heart Disease and Familiar Arrhythmias Unit, Monaldi Hospital, 80131 Naples, Italy.
Davide SoriceAdult Congenital Heart Disease and Familiar Arrhythmias Unit, Monaldi Hospital, 80131 Naples, Italy.
Lorenzo De LucaAdult Congenital Heart Disease and Familiar Arrhythmias Unit, Monaldi Hospital, 80131 Naples, Italy.
Giancarlo ScognamiglioAdult Congenital Heart Disease and Familiar Arrhythmias Unit, Monaldi Hospital, 80131 Naples, Italy.
Berardo SarubbiAdult Congenital Heart Disease and Familiar Arrhythmias Unit, Monaldi Hospital, 80131 Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in medical and surgical interventions have resulted in a steady increase in the number of patients with congenital heart disease (CHD) reaching adult age. Unfortunately, this ever-growing population faces an added challenge: an increased risk of acquiring coronary artery disease. This review provides insight into the complex interactions between coronary artery disease and CHD in adults. We describe the peculiar features of cardiac anatomy in these patients, the possible role cardiac sequelae may play in an increased risk of myocardial ischemia, and the diagnostic challenges in this patient group. Furthermore, this review outlines the risk factors and potential mechanisms of accelerated atherosclerosis in adults with CHD by pointing out areas where current knowledge is incomplete and highlighting areas for further research. The review concludes by examining potential management strategies for this particular population, emphasizing the necessity for a multidisciplinary approach. Understanding the unique coronary risks that adults with CHD experience can enhance patient care and improve long-term results.

Indexed as

atherosclerosiscardiovascular risk factorscongenital heart diseasecoronary artery disease

Identifiers

PMID39597982
PMCPMC11594384

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.