Evidence map›Paper›PMID 39598667›Full record

ArticleMolecules (Basel, Switzerland)2024

Cytotoxic and Antibacterial Activity of Koninginins Isolated from the Mangrove-Derived Endophytic Fungus

Gisele da Costa Ramos, Ingryd Nayara de Farias Ramos, Luciano Almeida Watanabe, Luciana Almeida Watanabe Castro, Alessandra Jackeline Guedes de Moraes, Gleiciane Rodrigues Dos Santos, José Edson de Sousa Siqueira, André Salim Khayat, Andrey Moacir do Rosario Marinho, Patrícia Santana Barbosa Marinho

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gisele da Costa RamosChemistry Graduate Program, Federal University of Pará, Rua Augusto Corrêa, 01, Belém 66075110, Brazil.
Ingryd Nayara de Farias RamosOncology Research Center, Federal University of Pará, Rua dos Mundurucus, 4487, Belém 66073005, Brazil.
Luciano Almeida WatanabeChemistry Graduate Program, Federal University of Pará, Rua Augusto Corrêa, 01, Belém 66075110, Brazil.
Luciana Almeida Watanabe CastroEvolution Laboratory, Federal University of Pará, Alameda Leandro Ribeiro, Bragança 68600000, Brazil.ORCID 0000-0003-3349-5508
Alessandra Jackeline Guedes de MoraesInstitute of Agricultural Sciences, Federal Rural University of the Amazon, Avenida Presidente Tancredo Neves, 2501, Belém 66077830, Brazil.
Gleiciane Rodrigues Dos SantosInstitute of Agricultural Sciences, Federal Rural University of the Amazon, Avenida Presidente Tancredo Neves, 2501, Belém 66077830, Brazil.
José Edson de Sousa SiqueiraChemistry Graduate Program, Federal University of Pará, Rua Augusto Corrêa, 01, Belém 66075110, Brazil.ORCID 0000-0003-1243-0799
André Salim KhayatOncology Research Center, Federal University of Pará, Rua dos Mundurucus, 4487, Belém 66073005, Brazil.ORCID 0000-0002-3451-6369
Andrey Moacir do Rosario MarinhoChemistry Graduate Program, Federal University of Pará, Rua Augusto Corrêa, 01, Belém 66075110, Brazil.ORCID 0000-0002-8981-0995
Patrícia Santana Barbosa MarinhoChemistry Graduate Program, Federal University of Pará, Rua Augusto Corrêa, 01, Belém 66075110, Brazil.ORCID 0000-0002-9368-8574

Funding

National Council for Scientific and Technological Development 308631/2021-8National Council for Scientific and Technological Development 310540/2022-4National Council for Scientific and Technological Development 406269/2022-0
6 · The paper itself

Abstract

The search for bioactive compounds for the treatment of several diseases has led to the study of endophytic fungi. Neoplastic diseases are among the most significant health concerns due to their high mortality rate, and there is a dearth of efficacious pharmaceutical agents for the treatment of cancer. Gastric cancer is one of the most aggressive forms of cancer and is among those with the highest mortality rates in Brazil. Accordingly, the objective of this study was to identify compounds with cytotoxic activity from the mangrove-derived endophytic fungus

Indexed as

Anti-Bacterial AgentsAntineoplastic AgentsTrichodermaCell Line, TumorEndophytesHumansMicrobial Sensitivity TestsRhizophoraceaeAnti-Bacterial AgentsAntineoplastic Agentsamazoncytotoxic activitykoningininsthichoderma

Identifiers

PMID39598667
PMCPMC11596921

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.