Evidence map›Paper›PMID 39600189›Full record

ArticleJournal of biophotonics2025

Effects of 1267 nm Illumination on Microcirculation Regulatory Mechanisms.

Lyubov Eratova, Irina Makovik, Viktor Dremin

Abstract read
In one paragraph

Article in Journal of biophotonics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lyubov EratovaR&D Center of Biomedical Photonics, Orel State University, Orel, Russia.
Irina MakovikR&D Center of Biomedical Photonics, Orel State University, Orel, Russia.
Viktor DreminR&D Center of Biomedical Photonics, Orel State University, Orel, Russia.

Funding

Russian Science Foundation 21-75-00086
6 · The paper itself

Abstract

This study explored the effects of 1267 nm laser irradiation on changes in blood flow parameters and activation of the regulatory mechanisms of the microcirculatory bed (MCB). Using laser Doppler flowmetry (LDF) technique and time-frequency analysis of perfusion signals, changes in the MCB of 16 healthy volunteers, targeting the distal phalanx of the third finger with 1267 nm laser irradiation were evaluated. Results indicated no significant differences in perfusion between control and target measurements, likely due to blood flow redistribution caused by vessel dilation/constriction. However, differences in oscillation amplitudes in endothelial and myogenic ranges were observed, suggesting microcirculation self-regulation. Detailed analysis revealed characteristic peaks in the endothelial range during and after irradiation, indicating endothelial mediator release. It is assumed that the identified effects may be related to the singlet oxygen generated by 1267 nm laser irradiation, which directly affects the MCB, manifesting as endothelium-dependent vascular activity.

Indexed as

LasersMicrocirculationAdultFemaleFingersHumansLaser-Doppler FlowmetryMaleYoung Adult1267 nm laserblood flow oscillationlaser Doppler flowmetrymicrocirculatory bedsinglet oxygenwavelet analysis

Identifiers

PMID39600189
PMCPMC12702645

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.